Jun Seung Baik1, Mi Hyun Lee1, Kook-Jin Ahn2, Hyun Seok Choi1, So Lyung Jung1, Bum-Soo Kim1, Sin Soo Jeun3, Yong-Kil Hong3. 1. Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, South Korea. 2. Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, South Korea. Electronic address: ahn-kj@catholic.ac.kr. 3. Department of Neurosurgery, Seoul St. Mary's Hospital, The Catholic University of Korea, South Korea.
Abstract
OBJECTIVE: To evaluate the correlation between the magnetic resonance imaging findings of functional pituitary adenomas and histological distribution of hormone-secreting cells in pituitary gland. METHODS: Forty-nine patients with pathologically confirmed functional micro and macro pituitary adenomas were retrospectively reviewed for its location and growth direction. RESULTS: Micro-prolactin, micro-adrenocorticotropic hormone (ACTH), and micro-growth hormone (GH) producing adenomas showed specific location (P-value <.01). Macro-GH and macro-thyroid-stimulating hormone producing adenomas showed specific growth direction (P-value <.05), whereas macro-prolactin and macro-ACTH producing adenomas did not. CONCLUSION: The functional pituitary microadenomas' location and macroadenomas' growth pattern correlate well with histological distribution of hormone-secreting cells in pituitary gland.
OBJECTIVE: To evaluate the correlation between the magnetic resonance imaging findings of functional pituitary adenomas and histological distribution of hormone-secreting cells in pituitary gland. METHODS: Forty-nine patients with pathologically confirmed functional micro and macro pituitary adenomas were retrospectively reviewed for its location and growth direction. RESULTS: Micro-prolactin, micro-adrenocorticotropic hormone (ACTH), and micro-growth hormone (GH) producing adenomas showed specific location (P-value <.01). Macro-GH and macro-thyroid-stimulating hormone producing adenomas showed specific growth direction (P-value <.05), whereas macro-prolactin and macro-ACTH producing adenomas did not. CONCLUSION: The functional pituitary microadenomas' location and macroadenomas' growth pattern correlate well with histological distribution of hormone-secreting cells in pituitary gland.
Authors: Stefanie Bette; Vicki M Butenschön; Benedikt Wiestler; Alexander von Werder; Roland M Schmid; Jens Lehmberg; Claus Zimmer; Bernhard Meyer; Jan S Kirschke; Jens Gempt Journal: Neurosurg Rev Date: 2018-11-13 Impact factor: 3.042
Authors: L Zubeldia-Brenner; C E Roselli; S E Recabarren; M C Gonzalez Deniselle; H E Lara Journal: J Neuroendocrinol Date: 2016-07 Impact factor: 3.627