| Literature DB >> 26115554 |
Venkata Krishnan1, Yuki Kasuya2, Qingmin Ji1, Marappan Sathish1, Lok Kumar Shrestha1, Shinsuke Ishihara3, Kosuke Minami1, Hiromi Morita4, Tomohiko Yamazaki4, Nobutaka Hanagata4, Kun'ichi Miyazawa5, Somobrata Acharya6, Waka Nakanishi1, Jonathan P Hill1, Katsuhiko Ariga1.
Abstract
A versatile method for the rapid fabrication of aligned fullerene C60 nanowhiskers (C60NWs) at the air-water interface is presented. This method is based on the vortex motion of a subphase (water), which directs floating C60NWs to align on the water surface according to the direction of rotational flow. Aligned C60NWs could be transferred onto many different flat substrates, and, in this case, aligned C60NWs on glass substrates were employed as a scaffold for cell culture. Bone forming human osteoblast MG63 cells adhered well to the C60NWs, and their growth was found to be oriented with the axis of the aligned C60NWs. Cells grown on aligned C60NWs were more highly oriented with the axis of alignment than when grown on randomly oriented nanowhiskers. A study of cell proliferation on the C60NWs revealed their low toxicity, indicating their potential for use in biomedical applications.Entities:
Keywords: air−water interface; alignment of nanostructures; cell culture; fullerene C60 nanowhiskers; vortex-flow-directed assembly
Mesh：
Substances：
Year: 2015 PMID： 26115554 DOI： 10.1021/acsami.5b04811
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN： 1944-8244 Impact factor: 9.229