Literature DB >> 26113531

Ebf1 in DNA repair and leukemogenesis.

Katia Georgopoulos1.   

Abstract

In this issue of Blood, Prasad et al provide evidence for a new role for the B-lineage transcriptional regulator early B-cell factor 1 (Ebf1) during early B-cell development and B-cell acute lymphoblastic leukemia (B-ALL).

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Year:  2015        PMID： 26113531      PMCID： PMC4481587          DOI： 10.1182/blood-2015-05-639427

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

1.  Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.

Authors:  Thomas Treiber; Elizabeth M Mandel; Sebastian Pott; Ildiko Györy; Sonja Firner; Edison T Liu; Rudolf Grosschedl
Journal:  Immunity       Date:  2010-05-06       Impact factor: 31.745

2.  Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.

Authors:  Ildiko Györy; Sören Boller; Robert Nechanitzky; Elizabeth Mandel; Sebastian Pott; Edison Liu; Rudolf Grosschedl
Journal:  Genes Dev       Date:  2012-03-19       Impact factor: 11.361

Review 3.  Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins.

Authors:  Rohit Prakash; Yu Zhang; Weiran Feng; Maria Jasin
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-04-01       Impact factor: 10.005

4.  Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.

Authors:  Mahadesh A J Prasad; Jonas Ungerbäck; Josefine Åhsberg; Rajesh Somasundaram; Tobias Strid; Malin Larsson; Robert Månsson; Ayla De Paepe; Henrik Lilljebjörn; Thoas Fioretos; James Hagman; Mikael Sigvardsson
Journal:  Blood       Date:  2015-04-02       Impact factor: 22.113

Review 5.  B-lineage transcription factors and cooperating gene lesions required for leukemia development.

Authors:  E Tijchon; J Havinga; F N van Leeuwen; B Scheijen
Journal:  Leukemia       Date:  2012-10-10       Impact factor: 11.528

Review 6.  Sources of DNA double-strand breaks and models of recombinational DNA repair.

Authors:  Anuja Mehta; James E Haber
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-08-07       Impact factor: 10.005

7.  Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.

Authors:  Josefine Åhsberg; Jonas Ungerbäck; Tobias Strid; Eva Welinder; Jenny Stjernberg; Malin Larsson; Hong Qian; Mikael Sigvardsson
Journal:  J Biol Chem       Date:  2013-09-27       Impact factor: 5.157

8.  High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

Authors:  R P Kuiper; E F P M Schoenmakers; S V van Reijmersdal; J Y Hehir-Kwa; A Geurts van Kessel; F N van Leeuwen; P M Hoogerbrugge
Journal:  Leukemia       Date:  2007-04-19       Impact factor: 11.528

9.  Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.

Authors:  Charles G Mullighan; Salil Goorha; Ina Radtke; Christopher B Miller; Elaine Coustan-Smith; James D Dalton; Kevin Girtman; Susan Mathew; Jing Ma; Stanley B Pounds; Xiaoping Su; Ching-Hon Pui; Mary V Relling; William E Evans; Sheila A Shurtleff; James R Downing
Journal:  Nature       Date:  2007-04-12       Impact factor: 49.962

Review 10.  The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function.

Authors:  Sören Boller; Rudolf Grosschedl
Journal:  Immunol Rev       Date:  2014-09       Impact factor: 12.988
  10 in total

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