Literature DB >> 26112246

Combined modified en bloc corpectomy with replacement of the aorta in curative interdisciplinary treatment of a large osteosarcoma infiltrating the aorta.

Amrei Pilger1, Nikolaos Tsilimparis2, Maximilian Bockhorn3, Martin Trepel4, Marc Dreimann5.   

Abstract

PURPOSE: We report a case of a large three-level spinal osteosarcoma infiltrating the adjacent aorta. This is the first case in which a combined modified three-level en bloc corpectomy with resection and replacement of the adjacent aorta was successful as a part of interdisciplinary curative treatment.
METHODS: Case report.
RESULTS: The surgical procedure was performed as a two-step treatment. A heart lung machine (HLM) was not used, in order to avoid cerebral and spinal ischemia and to decrease the risk of hematogenous tumor metastases. Instead, a bypass from the left subclavian artery the distal descending aorta was used. We modified the en bloc corpectomy procedure, leaving a dorsal segment of the vertebral bodies to enable rapid surgery. The procedure was successful and the en bloc resection of the vertebral body with aortal resection could be achieved. Except for pallhypesthesia in the left dermatomes Th7-Th10, the patient does not have any postoperative neurologic deficits.
CONCLUSION: Combined corpectomy with aortic replacement should be considered as a reasonable option in the curative treatment of osteosarcoma with consideration of the immense surgical risks. The use of an HLM is not necessary, especially considering the inherent risk of hematogenous tumor metastases. Modified corpectomy leaving a dorsal vertebral body segment was considered a reasonable variation since tumor-free margins could still be expected.

Entities:  

Keywords:  Aortic prosthesis; En bloc corpectomy; Resection of the aorta; Spinal osteosarcoma; Spinal tumor

Mesh:

Year:  2015        PMID: 26112246     DOI: 10.1007/s00586-015-4079-7

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  13 in total

1.  Surgical management of recurrent thoracolumbar spinal sarcoma with 4-level total en bloc spondylectomy: description of technique and report of two cases.

Authors:  Claudia Druschel; A C Disch; I Melcher; T Engelhardt; A Luzzati; N P Haas; K D Schaser
Journal:  Eur Spine J       Date:  2011-08-05       Impact factor: 3.134

2.  Four- and five- level en bloc spondylectomy for malignant spinal tumors.

Authors:  Alessandro D Luzzati; Sambhav P Shah; Fabio S Gagliano; Giuseppe G Perrucchini; Walter Fontanella; Marco Alloisio
Journal:  Spine (Phila Pa 1976)       Date:  2014-01-15       Impact factor: 3.468

Review 3.  Primary bone tumors of the spine. Terminology and surgical staging.

Authors:  S Boriani; J N Weinstein; R Biagini
Journal:  Spine (Phila Pa 1976)       Date:  1997-05-01       Impact factor: 3.468

Review 4.  Osteosarcoma.

Authors:  P A Meyers; R Gorlick
Journal:  Pediatr Clin North Am       Date:  1997-08       Impact factor: 3.278

5.  [Neoadjuvant therapy for localized osteosarcoma of extremities. Results from the Cooperative osteosarcoma study group COSS of 925 patients].

Authors:  S Bielack; B Kempf-Bielack; D Schwenzer; T Birkfellner; G Delling; V Ewerbeck; G U Exner; N Fuchs; U Göbel; N Graf; U Heise; K Helmke; A R von Hochstetter; H Jürgens; R Maas; N Münchow; M Salzer-Kuntschik; J Treuner; U Veltmann; M Werner; W Winkelmann; A Zoubek; R Kotz
Journal:  Klin Padiatr       Date:  1999 Jul-Aug       Impact factor: 1.349

6.  International patterns of cancer incidence in adolescents.

Authors:  Charles A Stiller
Journal:  Cancer Treat Rev       Date:  2007-02-27       Impact factor: 12.111

7.  Primary metastatic osteosarcoma: presentation and outcome of patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols.

Authors:  Leo Kager; Andreas Zoubek; Ulrike Pötschger; Ulrike Kastner; Silke Flege; Beate Kempf-Bielack; Detlev Branscheid; Rainer Kotz; Mechthild Salzer-Kuntschik; Winfried Winkelmann; Gernot Jundt; Hartmut Kabisch; Peter Reichardt; Heribert Jürgens; Helmut Gadner; Stefan S Bielack
Journal:  J Clin Oncol       Date:  2003-05-15       Impact factor: 44.544

8.  Osteosarcoma of the spine.

Authors:  T C Shives; D C Dahlin; F H Sim; D J Pritchard; J D Earle
Journal:  J Bone Joint Surg Am       Date:  1986-06       Impact factor: 5.284

9.  Bone cancers.

Authors:  H D Dorfman; B Czerniak
Journal:  Cancer       Date:  1995-01-01       Impact factor: 6.860

Review 10.  Spinal osteosarcoma.

Authors:  P Katonis; G Datsis; A Karantanas; A Kampouroglou; S Lianoudakis; S Licoudis; E Papoutsopoulou; K Alpantaki
Journal:  Clin Med Insights Oncol       Date:  2013-08-18
View more
  2 in total

1.  Interdisciplinary Surgical Treatments and Long-Term Outcomes of Lumbar Spinal Tumors With Retroperitoneal Involvements: A Retrospective Case Series Study.

Authors:  Shaohui He; Yifeng Bi; Chen Ye; Dongyu Peng; Jianru Xiao; Haifeng Wei
Journal:  Front Oncol       Date:  2021-12-23       Impact factor: 6.244

Review 2.  A Radiologists' Guide to En Bloc Resection of Primary Tumors in the Spine: What Does the Surgeon Want to Know?

Authors:  E Smith; G Hegde; M Czyz; S Hughes; S Haleem; M Grainger; S L James; R Botchu
Journal:  Indian J Radiol Imaging       Date:  2022-06-09
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.