Literature DB >> 2611091

Lithium inhibits human sperm motility in vitro.

N T Raoof1, R M Pearson, P Turner.   

Abstract

Lithium is a widely prescribed drug used for the treatment of bipolar affective illness. Previous reports on its effects on sperm motility and male fertility are conflicting. The effect of lithium on human sperm motility was examined in vitro using the modified transmembrane migration method. This technique takes account of the dilution of lithium that occurs during the incubation. Lithium inhibits human sperm motility in vitro in concentrations comparable with those reported to be achieved in semen after oral administration.

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Year:  1989        PMID： 2611091      PMCID： PMC1380043          DOI： 10.1111/j.1365-2125.1989.tb03565.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  10 in total

1.  THE RELATIONSHIP OF SWIMMING MOVEMENTS OF EPIDIDYMAL SPERMATOZOA TO THEIR FERTILIZING CAPACITY.

Authors:  R J BLANDAU; R E RUMERY
Journal:  Fertil Steril       Date:  1964 Nov-Dec       Impact factor: 7.329

2.  Swimming rate of bull spermatozoa in various media and the effect of dilution.

Authors:  D TAMPION; R A GIBBONS
Journal:  J Reprod Fertil       Date:  1963-04

3.  Measurement of boar sperm motility by the trans-membrane migration method.

Authors:  S L Lee; C Sun; J H Lin; C Y Hong; Y H Wei
Journal:  Proc Natl Sci Counc Repub China B       Date:  1989-04

4.  A modified trans-membrane migration method for measuring the effect of drugs on sperm motility.

Authors:  N T Raoof; R M Pearson; P Turner
Journal:  Br J Clin Pharmacol       Date:  1987-09       Impact factor: 4.335

Review 5.  Sperm motility.

Authors:  R D Amelar; L Dubin; C Schoenfeld
Journal:  Fertil Steril       Date:  1980-09       Impact factor: 7.329

6.  Lithium reversibly inhibits microtubule-based motility in sperm flagella.

Authors:  B H Gibbons; I R Gibbons
Journal:  Nature       Date:  1984 Jun 7-13       Impact factor: 49.962

7.  Lithium levels in the ejaculate, spermiogram and adjuvant psychopharmacological therapy.

Authors:  M Kolomazník; J Sůva; D Svejnohová; I Janousek; F Sefrna
Journal:  Act Nerv Super (Praha)       Date:  1981-12

8.  Spermiologic findings during longterm lithium therapy.

Authors:  J Raboch; P Smolík; K Soucek; J Raboch; R Krulík
Journal:  Act Nerv Super (Praha)       Date:  1981-12

9.  A simple method to measure drug effects on human sperm motility.

Authors:  C Y Hong; D M Chaput de Saintonge; P Turner
Journal:  Br J Clin Pharmacol       Date:  1981-04       Impact factor: 4.335

10.  Effects of psychotropic drugs on human sperm motility.

Authors:  R M Levin; J D Amsterdam; A Winokur; A J Wein
Journal:  Fertil Steril       Date:  1981-10       Impact factor: 7.329
  10 in total
  3 in total

1.  Pentoxifylline stimulates human sperm motility both in vitro and after oral therapy.

Authors:  M R Shen; P H Chiang; R C Yang; C Y Hong; S S Chen
Journal:  Br J Clin Pharmacol       Date:  1991-06       Impact factor: 4.335

2.  The Role of Mitochondrial Impairment and Oxidative Stress in the Pathogenesis of Lithium-Induced Reproductive Toxicity in Male Mice.

Authors:  Mohammad Mehdi Ommati; Mohammad Reza Arabnezhad; Omid Farshad; Akram Jamshidzadeh; Hossein Niknahad; Socorro Retana-Marquez; Zhipeng Jia; Mohammad Hassan Nateghahmadi; Khadijeh Mousavi; Aysooda Arazi; Mohammad Reza Azmoon; Negar Azarpira; Reza Heidari
Journal:  Front Vet Sci       Date:  2021-03-24

3.  Lithium carbonate inducing disorders in three parameters of rat sperm.

Authors:  Shima Toghyani; Gholam R Dashti; Nasim Hayati Roudbari; Shaila Rouzbehani; Ramesh Monajemi
Journal:  Adv Biomed Res       Date:  2013-07-30
  3 in total

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