Literature DB >> 26109386

Developing Peripheral Blood Gene Expression-Based Diagnostic Tests for Coronary Artery Disease: a Review.

Brian Rhees1, James A Wingrove.   

Abstract

The past 20 years has witnessed the development of technologies designed to measure changes in the expressed human genome, including the levels of RNA transcripts, proteins, and metabolites. Gene expression profiling, or the measurement of RNA transcripts, allows investigators to obtain a snapshot of a subject's current physiological state and may be used to assess disease likelihood. In this review, we provide an overview of recent work using peripheral blood gene expression to assess coronary artery disease (CAD) and discuss the best approaches for developing and validating tests utilizing such gene expression signatures.

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Year:  2015        PMID： 26109386     DOI： 10.1007/s12265-015-9641-5

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN： 1937-5387            Impact factor:   4.132


  58 in total

1.  Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients.

Authors:  Steven Rosenberg; Michael R Elashoff; Philip Beineke; Susan E Daniels; James A Wingrove; Whittemore G Tingley; Philip T Sager; Amy J Sehnert; May Yau; William E Kraus; L Kristin Newby; Robert S Schwartz; Szilard Voros; Stephen G Ellis; Naeem Tahirkheli; Ron Waksman; John McPherson; Alexandra Lansky; Mary E Winn; Nicholas J Schork; Eric J Topol
Journal:  Ann Intern Med       Date:  2010-10-05       Impact factor: 25.391

2.  Theoretical basis of the Beavis effect.

Authors:  Shizhong Xu
Journal:  Genetics       Date:  2003-12       Impact factor: 4.562

3.  Which white blood cell subtypes predict increased cardiovascular risk?

Authors:  Benjamin D Horne; Jeffrey L Anderson; Jerry M John; Aaron Weaver; Tami L Bair; Kurt R Jensen; Dale G Renlund; Joseph B Muhlestein
Journal:  J Am Coll Cardiol       Date:  2005-04-25       Impact factor: 24.094

Review 4.  Multiple roles for neutrophils in atherosclerosis.

Authors:  Oliver Soehnlein
Journal:  Circ Res       Date:  2012-03-16       Impact factor: 17.367

5.  Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.

Authors:  Lorna W Harries; Dena Hernandez; William Henley; Andrew R Wood; Alice C Holly; Rachel M Bradley-Smith; Hanieh Yaghootkar; Ambarish Dutta; Anna Murray; Timothy M Frayling; Jack M Guralnik; Stefania Bandinelli; Andrew Singleton; Luigi Ferrucci; David Melzer
Journal:  Aging Cell       Date:  2011-07-19       Impact factor: 9.304

Review 6.  The role of T and B cells in human atherosclerosis and atherothrombosis.

Authors:  E Ammirati; F Moroni; M Magnoni; P G Camici
Journal:  Clin Exp Immunol       Date:  2015-02       Impact factor: 4.330

7.  Biomarker discovery for heterogeneous diseases.

Authors:  Garrick Wallstrom; Karen S Anderson; Joshua LaBaer
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2013-03-05       Impact factor: 4.254

8.  Bias in error estimation when using cross-validation for model selection.

Authors:  Sudhir Varma; Richard Simon
Journal:  BMC Bioinformatics       Date:  2006-02-23       Impact factor: 3.169

9.  A meta-analysis of gene expression signatures of blood pressure and hypertension.

Authors:  Tianxiao Huan; Tõnu Esko; Marjolein J Peters; Luke C Pilling; Katharina Schramm; Claudia Schurmann; Brian H Chen; Chunyu Liu; Roby Joehanes; Andrew D Johnson; Chen Yao; Sai-Xia Ying; Paul Courchesne; Lili Milani; Nalini Raghavachari; Richard Wang; Poching Liu; Eva Reinmaa; Abbas Dehghan; Albert Hofman; André G Uitterlinden; Dena G Hernandez; Stefania Bandinelli; Andrew Singleton; David Melzer; Andres Metspalu; Maren Carstensen; Harald Grallert; Christian Herder; Thomas Meitinger; Annette Peters; Michael Roden; Melanie Waldenberger; Marcus Dörr; Stephan B Felix; Tanja Zeller; Ramachandran Vasan; Christopher J O'Donnell; Peter J Munson; Xia Yang; Holger Prokisch; Uwe Völker; Joyce B J van Meurs; Luigi Ferrucci; Daniel Levy
Journal:  PLoS Genet       Date:  2015-03-18       Impact factor: 5.917

10.  Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.

Authors:  Saara Marttila; Juulia Jylhävä; Tapio Nevalainen; Matti Nykter; Marja Jylhä; Antti Hervonen; Liina Tserel; Pärt Peterson; Mikko Hurme
Journal:  PLoS One       Date:  2013-06-11       Impact factor: 3.240
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  3 in total

1.  Whole blood transcriptome profile at hospital admission discriminates between patients with ST-segment elevation and non-ST-segment elevation acute myocardial infarction.

Authors:  Mattia Chiesa; Luca Piacentini; Elisa Bono; Valentina Milazzo; Jeness Campodonico; Giancarlo Marenzi; Gualtiero I Colombo
Journal:  Sci Rep       Date:  2020-05-26       Impact factor: 4.379

Review 2.  Circulating Leukocytes and Oxidative Stress in Cardiovascular Diseases: A State of the Art.

Authors:  Speranza Rubattu; Maurizio Forte; Salvatore Raffa
Journal:  Oxid Med Cell Longev       Date:  2019-10-15       Impact factor: 6.543

3.  Circulating Extracellular Vesicles Contain miRNAs and are Released as Early Biomarkers for Cardiac Injury.

Authors:  Janine C Deddens; Krijn R Vrijsen; Johanna M Colijn; Martinus I Oerlemans; Corina H G Metz; Els J van der Vlist; Esther N M Nolte-'t Hoen; Krista den Ouden; Sanne J Jansen Of Lorkeers; Tycho I G van der Spoel; Stefan Koudstaal; Ger J Arkesteijn; Marca H M Wauben; Linda W van Laake; Pieter A Doevendans; Steven A J Chamuleau; Joost P G Sluijter
Journal:  J Cardiovasc Transl Res       Date:  2016-07-06       Impact factor: 4.132
  3 in total

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