Literature DB >> 26108560

Long-term functional airway assessment after open airway surgery for laryngotracheal stenosis.

Bas Pullens1, Marielle W Pijnenburg2, Hans J Hoeve1, Rob J Baatenburg de Jong1, Corinne M P Buysse3, Marieke K Timmerman1, Marc P van der Schroeff1, Koen F M Joosten3.   

Abstract

OBJECTIVES/HYPOTHESIS: The purpose of this study was to evaluate our patient-reported and objective long-term outcomes of patients treated for laryngotracheal stenosis. STUDY
DESIGN: Prospective cohort study.
METHODS: Sixty-five patients were evaluated after a median follow-up of 7 years after surgery. Follow-up measurements consisted of pulmonary function testing, Bruce treadmill test, and Child Health Questionnaires (CHQ).
RESULTS: Pulmonary function tests were available in 43 patients, and 30/43 had abnormal forced expiratory volume in 1 second/forced inspiratory volume in 1 second (FIV1), 25/43 had abnormal FIV1/maximum vital capacity, and 24/43 had abnormal peak expiratory flow. One-third of patients had reduced exercise tolerance. CHQ revealed significant positive correlations with pulmonary function results and exercise tolerance. Multivariate analysis showed that glottic involvement of the stenosis and the presence of comorbidities at time of surgery are the only factors for poor long-term functional outcome.
CONCLUSIONS: The majority of patients show deficits in pulmonary function and exercise tolerance related to lower scores of quality of life. Glottic involvement of the stenosis and the presence of comorbidities are the only significant factors for poor functional outcome. Long-term multidisciplinary follow up is mandatory after surgery for laryngotracheal stenosis. LEVEL OF EVIDENCE: 2B.
© 2015 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Laryngotracheal stenosis; children; cricotracheal resection; functional outcome; laryngotracheal reconstruction; surgical results

Mesh:

Year:  2015        PMID: 26108560     DOI: 10.1002/lary.25419

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  1 in total

1.  MRI of the upper airways in children and young adults: the MUSIC study.

Authors:  Bernadette Elders; Pierluigi Ciet; Harm Tiddens; Wytse van den Bosch; Piotr Wielopolski; Bas Pullens
Journal:  Thorax       Date:  2020-10-29       Impact factor: 9.139

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.