Literature DB >> 26107758

Endothelial Keratoplasty: A Review of Indications at a Tertiary Eye Care Centre in South India.

Ashik Mohamed1, Sunita Chaurasia, Somasheila I Murthy, Muralidhar Ramappa, Pravin K Vaddavalli, Mukesh Taneja, Prashant Garg, Supriya Chinta, Sayan Basu, Varsha M Rathi, Virender S Sangwan.   

Abstract

PURPOSE: The objective of this study was to review the indications for endothelial keratoplasty (EK) performed at a tertiary eye care center in South India between January 2007 and December 2011.
DESIGN: This was a hospital-based, cross-sectional study.
METHODS: A retrospective analysis of the indications of EK surgeries between January 2007 and December 2011 was done using the Corneal Tissue Utilization Register available with the Ramayamma International Eye Bank, L. V. Prasad Eye Institute, Hyderabad, India. Additional data such as age, sex, and socioeconomic status of the transplant recipients were obtained from the Medical Records Department, L. V. Prasad Eye Institute.
RESULTS: Data were available for 1048 EK surgeries performed on 978 patients. The number of EK surgeries increased from 40 in 2007 to 232 in 2011. The median age of the patients was 58 years (range, 5 months to 92 years) with a male-female ratio of 1.5:1. The clinical indications for EK were pseudophakic corneal edema (47.9%), failed prior penetrating keratoplasty (20.0%), Fuchs endothelial corneal dystrophy (10.8%), aphakic corneal edema (6.0%), failed prior EK (4.3%), congenital hereditary endothelial dystrophy (1.8%), Descemet membrane detachment/tear (1.6%), iridocorneal endothelial syndrome (1.4%), and corneal edema due to other reasons (6.2%).
CONCLUSIONS: The most common indication for EK was pseudophakic corneal edema, followed by post-penetrating keratoplasty graft failure and Fuchs endothelial corneal dystrophy.

Entities:  

Year:  2014        PMID: 26107758     DOI: 10.1097/APO.0b013e3182a75304

Source DB:  PubMed          Journal:  Asia Pac J Ophthalmol (Phila)        ISSN: 2162-0989


  7 in total

1.  Outcomes of Descemet Membrane Endothelial Keratoplasty in Bangkok, Thailand.

Authors:  Kaevalin Lekhanont; Punyanuch Pisitpayat; Nontawat Cheewaruangroj; Passara Jongkhajornpong; Manachai Nonpassopon; Thunyarat Anothaisintawee
Journal:  Clin Ophthalmol       Date:  2021-05-31

Review 2.  Iridocorneal endothelial syndrome: clinical perspectives.

Authors:  Andrew Walkden; Leon Au
Journal:  Clin Ophthalmol       Date:  2018-04-09

3.  rs4246215 is targeted by hsa-miR1236 to regulate FEN1 expression but is not associated with Fuchs' endothelial corneal dystrophy.

Authors:  Gargi Gouranga Nanda; Malloji Vinay Kumar; Laxmipriya Pradhan; Biswajit Padhy; Satabdi Sundaray; Sujata Das; Debasmita Pankaj Alone
Journal:  PLoS One       Date:  2018-09-27       Impact factor: 3.240

Review 4.  REVIEW: Current understanding of the pathogenesis of Fuchs' endothelial corneal dystrophy.

Authors:  Gargi Gouranga Nanda; Debasmita Pankaj Alone
Journal:  Mol Vis       Date:  2019-06-05       Impact factor: 2.367

Review 5.  Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis.

Authors:  Stephan Ong Tone; Viridiana Kocaba; Myriam Böhm; Adam Wylegala; Tomas L White; Ula V Jurkunas
Journal:  Prog Retin Eye Res       Date:  2020-05-08       Impact factor: 21.198

6.  Outcomes of therapeutic penetrating keratoplasty in 198 eyes with fungal keratitis.

Authors:  Jyothi Mundra; Rohit Dhakal; Ashik Mohamed; Govinda Jha; Joveeta Joseph; Sunita Chaurasia; Somasheila Murthy
Journal:  Indian J Ophthalmol       Date:  2019-10       Impact factor: 1.848

7.  Overall clinical outcomes of Descemet membrane endothelial keratoplasty in 600 consecutive eyes: A large retrospective case series.

Authors:  Samar K Basak; Soham Basak; Nidhi Gajendragadkar; Mrinmoyee Ghatak
Journal:  Indian J Ophthalmol       Date:  2020-06       Impact factor: 1.848

  7 in total

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