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6 in total

1. AT-1001: a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats.

Authors: Lawrence Toll; Nurulain T Zaveri; Willma E Polgar; Faming Jiang; Taline V Khroyan; Wei Zhou; Xinmin Simon Xie; Gregory B Stauber; Matthew R Costello; Frances M Leslie
Journal: Neuropsychopharmacology Date: 2012-01-25 Impact factor: 7.853

2. Dynamic vaccine blocks relapse to compulsive intake of heroin.

Authors: Joel E Schlosburg; Leandro F Vendruscolo; Paul T Bremer; Jonathan W Lockner; Carrie L Wade; Ashlee A K Nunes; G Neil Stowe; Scott Edwards; Kim D Janda; George F Koob
Journal: Proc Natl Acad Sci U S A Date: 2013-05-06 Impact factor: 11.205

Review 3. A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse.

Authors: Linda P Dwoskin; Peter A Crooks
Journal: Biochem Pharmacol Date: 2002-01-15 Impact factor: 5.858

4. Pharmacological stress is required for the anti-alcohol effect of the α3β4* nAChR partial agonist AT-1001.

Authors: Andrea Cippitelli; Gloria Brunori; Kelly A Gaiolini; Nurulain T Zaveri; Lawrence Toll
Journal: Neuropharmacology Date: 2015-02-14 Impact factor: 5.250

5. 18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats.

Authors: S D Glick; M E Kuehne; I M Maisonneuve; U K Bandarage; H H Molinari
Journal: Brain Res Date: 1996-05-06 Impact factor: 3.252

6. 18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens.

Authors: Olga D Taraschenko; Joseph M Shulan; Isabelle M Maisonneuve; Stanley D Glick
Journal: Synapse Date: 2007-07 Impact factor: 2.562

6 in total

11 in total

1. Effectiveness of a Cocaine Hydrolase for Cocaine Toxicity Treatment in Male and Female Rats.

Authors: Xirong Zheng; Ziyuan Zhou; Ting Zhang; Zhenyu Jin; Xiabin Chen; Jing Deng; Chang-Guo Zhan; Fang Zheng
Journal: AAPS J Date: 2017-11-27 Impact factor: 4.009

2. Long-acting cocaine hydrolase for addiction therapy.

Authors: Xiabin Chen; Liu Xue; Shurong Hou; Zhenyu Jin; Ting Zhang; Fang Zheng; Chang-Guo Zhan
Journal: Proc Natl Acad Sci U S A Date: 2015-12-28 Impact factor: 11.205

3. Effects of a cocaine hydrolase engineered from human butyrylcholinesterase on metabolic profile of cocaine in rats.

Authors: Xiabin Chen; Xirong Zheng; Ziyuan Zhou; Chang-Guo Zhan; Fang Zheng
Journal: Chem Biol Interact Date: 2016-05-03 Impact factor: 5.192

4. Development of Fc-Fused Cocaine Hydrolase for Cocaine Addiction Treatment: Catalytic and Pharmacokinetic Properties.

Authors: Xiabin Chen; Jing Deng; Wenpeng Cui; Shurong Hou; Jinling Zhang; Xirong Zheng; Xin Ding; Huimei Wei; Ziyuan Zhou; Kyungbo Kim; Chang-Guo Zhan; Fang Zheng
Journal: AAPS J Date: 2018-03-19 Impact factor: 4.009

5. Structure-Based Design and Discovery of a Long-Acting Cocaine Hydrolase Mutant with Improved Binding Affinity to Neonatal Fc Receptor for Treatment of Cocaine Abuse.

Authors: Fang Zheng; Xiabin Chen; Kyungbo Kim; Ting Zhang; Haifeng Huang; Shuo Zhou; Jinling Zhang; Zhenyu Jin; Chang-Guo Zhan
Journal: AAPS J Date: 2020-03-18 Impact factor: 4.009

6. Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life.

Authors: Yingting Cai; Shuo Zhou; Zhenyu Jin; Huimei Wei; Linyue Shang; Jing Deng; Chang-Guo Zhan; Fang Zheng
Journal: AAPS J Date: 2019-11-21 Impact factor: 4.009

7. Unexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of "hunger hormone" ghrelin.

Authors: Jianzhuang Yao; Yaxia Yuan; Fang Zheng; Chang-Guo Zhan
Journal: Sci Rep Date: 2016-02-29 Impact factor: 4.379

8. Clinical Potential of an Enzyme-based Novel Therapy for Cocaine Overdose.

Authors: Ting Zhang; Xirong Zheng; Ziyuan Zhou; Xiabin Chen; Zhenyu Jin; Jing Deng; Chang-Guo Zhan; Fang Zheng
Journal: Sci Rep Date: 2017-11-10 Impact factor: 4.379

9. Clinical potential of a rationally engineered enzyme for treatment of cocaine dependence: Long-lasting blocking of the psychostimulant, discriminative stimulus, and reinforcing effects of cocaine.

Authors: Ting Zhang; Huimei Wei; Jing Deng; Fang Zheng; Chang-Guo Zhan
Journal: Neuropharmacology Date: 2020-07-22 Impact factor: 5.250

10. Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse.

Authors: Guojun Wang; Ting Zhang; Haifeng Huang; Shurong Hou; Xiabin Chen; Fang Zheng; Chang-Guo Zhan
Journal: BMC Biotechnol Date: 2016-10-19 Impact factor: 2.563