Literature DB >> 26106161

Less than the sum of its parts, a leinamycin precursor has superior properties.

William P Katt1, Richard A Cerione2.   

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Year:  2015        PMID： 26106161      PMCID： PMC4500279          DOI： 10.1073/pnas.1510122112

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  8 in total

1.  Natural product synthesis and vitamin B12.

Authors:  A Eschenmoser; C E Wintner
Journal:  Science       Date:  1977-06-24       Impact factor: 47.728

2.  The total synthesis of vitamin B 12 .

Authors:  R B Woodward
Journal:  Pure Appl Chem       Date:  1973       Impact factor: 2.453

3.  Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.

Authors:  C Vézina; A Kudelski; S N Sehgal
Journal:  J Antibiot (Tokyo)       Date:  1975-10       Impact factor: 2.649

4.  Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species.

Authors:  Sheng-Xiong Huang; Bong-Sik Yun; Ming Ma; Hirak S Basu; Dawn R Church; Gudrun Ingenhorst; Yong Huang; Dong Yang; Jeremy R Lohman; Gong-Li Tang; Jianhua Ju; Tao Liu; George Wilding; Ben Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-08       Impact factor: 11.205

5.  Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast.

Authors:  J Heitman; N R Movva; M N Hall
Journal:  Science       Date:  1991-08-23       Impact factor: 47.728

6.  Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase.

Authors:  Gong-Li Tang; Yi-Qiang Cheng; Ben Shen
Journal:  Chem Biol       Date:  2004-01

7.  Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140.

Authors:  Yi-Qiang Cheng; Gong-Li Tang; Ben Shen
Journal:  J Bacteriol       Date:  2002-12       Impact factor: 3.490

8.  Leinamycin, a new antitumor antibiotic from Streptomyces: producing organism, fermentation and isolation.

Authors:  M Hara; K Asano; I Kawamoto; T Takiguchi; S Katsumata; K Takahashi; H Nakano
Journal:  J Antibiot (Tokyo)       Date:  1989-12       Impact factor: 2.649
  8 in total

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