Andrea V Das Neves1, Daniela N Vasquez2, Cecilia I Loudet1, Dante Intile2, María Gabriela Sáenz1, Cecilia Marchena1, Ana L Gonzalez1, Joaquin Moreira3, Rosa Reina1, Elisa Estenssoro4. 1. Servicio de Terapia Intensiva, Hospital Interzonal General de Agudos San Martin de La Plata 1 y 70, 1900 La Plata, Buenos Aires, Argentina. 2. Servicio de Terapia Intensiva, Sanatorio Anchorena, Tomas de Anchorena, C1425ELP, 1872 Ciudad Autónoma de Buenos Aires, Argentina. 3. Instituto del Diagnostico, 62 n° 370, 1900 La Plata, Buenos Aires, Argentina. 4. Servicio de Terapia Intensiva, Hospital Interzonal General de Agudos San Martin de La Plata 1 y 70, 1900 La Plata, Buenos Aires, Argentina. Electronic address: estenssoro.elisa@gmail.com.
Abstract
PURPOSE: Our goal was to describe the evolution of selected physical and psychologic symptoms and identify the determinants of health-related quality of life (HRQOL) after intensive care unit (ICU) discharge. METHODS: The study is a prospective cohort of consecutive adult patients admitted to a mixed ICU in a university-affiliated hospital, mechanically ventilated for more than 48 hours. During ICU stay, epidemiological data and events probably associated to worsening outcomes were recorded. After discharge, patients were interviewed at 1, 3, 6, and 12 months. Health-related quality of life was assessed with EuroQoL Questionnaire-5 Dimensions, which includes the EQ-index and EQ-Visual Analogue Scale. RESULTS: One hundred twelve patients were followed up, aged 33 [24-49] years, 68% male, 76% previously healthy, and cranial trauma was the main diagnosis. Physical and psychologic symptoms and moderate/severe problems according to the EQ index progressively decreased after discharge, yet were still highly prevalent after 1 year. EQ index improved from 0.22 [0.01-0.69] to 0.52 [0.08-0.81], 0.66 [0.17-0.79], and 0.68 [0.26-0.86] (P < .001, for all vs month 1). EQ-Visual Analogue Scale remained stable, within acceptable values. Independent determinants of EQ-index were time, duration of mechanical ventilation, shock, weakness, and return to study/work. CONCLUSIONS: Determinants of HRQOL after ICU discharge were both related to late sequelae of critical illness and to some events occurring in the ICU. Notwithstanding the high symptom burden, patients still perceived their HRQOL as good.
PURPOSE: Our goal was to describe the evolution of selected physical and psychologic symptoms and identify the determinants of health-related quality of life (HRQOL) after intensive care unit (ICU) discharge. METHODS: The study is a prospective cohort of consecutive adult patients admitted to a mixed ICU in a university-affiliated hospital, mechanically ventilated for more than 48 hours. During ICU stay, epidemiological data and events probably associated to worsening outcomes were recorded. After discharge, patients were interviewed at 1, 3, 6, and 12 months. Health-related quality of life was assessed with EuroQoL Questionnaire-5 Dimensions, which includes the EQ-index and EQ-Visual Analogue Scale. RESULTS: One hundred twelve patients were followed up, aged 33 [24-49] years, 68% male, 76% previously healthy, and cranial trauma was the main diagnosis. Physical and psychologic symptoms and moderate/severe problems according to the EQ index progressively decreased after discharge, yet were still highly prevalent after 1 year. EQ index improved from 0.22 [0.01-0.69] to 0.52 [0.08-0.81], 0.66 [0.17-0.79], and 0.68 [0.26-0.86] (P < .001, for all vs month 1). EQ-Visual Analogue Scale remained stable, within acceptable values. Independent determinants of EQ-index were time, duration of mechanical ventilation, shock, weakness, and return to study/work. CONCLUSIONS: Determinants of HRQOL after ICU discharge were both related to late sequelae of critical illness and to some events occurring in the ICU. Notwithstanding the high symptom burden, patients still perceived their HRQOL as good.
Authors: Selina M Parry; Swaroopa R Nalamalapu; Krishidhar Nunna; Anahita Rabiee; Lisa Aronson Friedman; Elizabeth Colantuoni; Dale M Needham; Victor D Dinglas Journal: J Intensive Care Med Date: 2019-11-05 Impact factor: 3.510
Authors: Cecilia Inés Loudet; María Cecilia Marchena; María Roxana Maradeo; Silvia Laura Fernández; María Victoria Romero; Graciela Esther Valenzuela; Isabel Eustaquia Herrera; Martha Teresa Ramírez; Silvia Rojas Palomino; Mariana Virginia Teberobsky; Leandro Ismael Tumino; Ana Laura González; Rosa Reina; Elisa Estenssoro Journal: Rev Bras Ter Intensiva Date: 2017 Jan-Mar
Authors: Paula Caitano Fontela; Franciele Aline Norberto Branquinho Abdala; Soraia Genebra Ibrahim Forgiarini; Luiz Alberto Forgiarini Journal: Rev Bras Ter Intensiva Date: 2018 Oct-Dec