| Literature DB >> 26101939 |
Christian Rösner1, Ulrich Hennecke1.
Abstract
An efficient method for the halocyclization of cyclopropanes has been developed. The cyclopropanes undergo a 1,3-addition reaction to form homohalocyclization products compared to conventional alkene halocyclizations. The reaction can be induced by various electrophilic halogenating agents including 1,3-dibromo-5,5-dimethylhydantoin and N-iodosuccinimide. In cyclopropane derivatives with a preexisting stereocenter, excellent induced diastereoselectivities can be observed.Entities:
Year: 2015 PMID： 26101939 DOI： 10.1021/acs.orglett.5b01315
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005