Literature DB >> 26100698

In vitro activities of a wide panel of antifungal drugs against various Scopulariopsis and Microascus species.

Magdalena Skóra1, Małgorzata Bulanda2, Tomasz Jagielski3.   

Abstract

The in vitro activities of 11 antifungal drugs against 68 Scopulariopsis and Microascus strains were investigated. Amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, ketoconazole, miconazole, posaconazole, voriconazole, and ciclopirox showed no or poor antifungal effect. The best activities were exhibited by terbinafine and caspofungin, where the MIC and MEC (minimal effective concentration) ranges were 0.0313 to >16 μg/ml and 0.125 to 16 μg/ml, respectively. The MIC and MEC modes were both 1 µg/ml for terbinafine and caspofungin; the MIC50 and MEC50 were 1 µg/ml for both drugs, whereas the MIC90 and MEC90 were 4 µg/ml and 16 µg/ml, respectively.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 26100698      PMCID： PMC4538558          DOI： 10.1128/AAC.00978-15

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

1.  In vitro antifungal susceptibilities of Scopulariopsis isolates.

Authors:  C Aguilar; I Pujol; J Guarro
Journal:  Antimicrob Agents Chemother       Date:  1999-06       Impact factor: 5.191

2.  Disseminated Scopulariopsis brevicaulis infection in an allogeneic stem cell recipient.

Authors:  M Vignon; D Michonneau; M-T Baixench; C Al-Nawakil; D Bouscary; A Buzyn; D Salmon; A Paugam
Journal:  Bone Marrow Transplant       Date:  2010-11-29       Impact factor: 5.483

3.  Scopulariopsis, a poorly known opportunistic fungus: spectrum of species in clinical samples and in vitro responses to antifungal drugs.

Authors:  Marcelo Sandoval-Denis; Deanna A Sutton; Annette W Fothergill; Josep Cano-Lira; Josepa Gené; C A Decock; G S de Hoog; Josep Guarro
Journal:  J Clin Microbiol       Date:  2013-09-11       Impact factor: 5.948

4.  In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

Authors:  Manuel Cuenca-Estrella; Alicia Gomez-Lopez; Maria J Buitrago; Emilia Mellado; Guillermo Garcia-Effron; Juan L Rodriguez-Tudela
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

5.  In vitro activity of voriconazole against dermatophytes, Scopulariopsis brevicaulis and other opportunistic fungi as agents of onychomycosis.

Authors:  A J Carrillo-Muñoz; G Giusiano; J Guarro; G Quindós; C Guardia; O del Valle; V Rodríguez; D Estivill; C D Cárdenes
Journal:  Int J Antimicrob Agents       Date:  2007-06-06       Impact factor: 5.283

6.  In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi.

Authors:  Manuel Cuenca-Estrella; Alicia Gomez-Lopez; Emilia Mellado; Guillermo Garcia-Effron; Araceli Monzon; Juan Luis Rodriguez-Tudela
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

7.  Microascus cinereus (Anamorph scopulariopsis) brain abscess in a bone marrow transplant recipient.

Authors:  J W Baddley; S A Moser; D A Sutton; P G Pappas
Journal:  J Clin Microbiol       Date:  2000-01       Impact factor: 5.948

8.  [Antifungal susceptibility of clinical isolates of Scopulariopsis species].

Authors:  V Odero; L García-Agudo; I Guerrero; P Aznar; P García-Martos; M Rodríguez-Iglesias
Journal:  Rev Esp Quimioter       Date:  2014-03       Impact factor: 1.553

9.  In vitro antifungal susceptibility of Scopulariopsis brevicaulis isolates.

Authors:  Magdalena Skóra; Anna B Macura; Małgorzata Bulanda
Journal:  Med Mycol       Date:  2014-07-21       Impact factor: 4.076

10.  Head-to-head comparison of the activities of currently available antifungal agents against 3,378 Spanish clinical isolates of yeasts and filamentous fungi.

Authors:  Manuel Cuenca-Estrella; Alicia Gomez-Lopez; Emilia Mellado; Maria J Buitrago; Araceli Monzon; Juan Luis Rodriguez-Tudela
Journal:  Antimicrob Agents Chemother       Date:  2006-03       Impact factor: 5.191
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  5 in total

1.  Virulence and Resistance to Antifungal Therapies of Scopulariopsis Species.

Authors:  Katihuska Paredes; Javier Capilla; Emilio Mayayo; Josep Guarro
Journal:  Antimicrob Agents Chemother       Date:  2016-03-25       Impact factor: 5.191

2.  Invasive cutaneous infection due to Scopulariopsis brevicaulis unsuccessfully treated with high-dose micafungin in a neutropenic patient.

Authors:  Daniela Gavril; Paul-Louis Woerther; Aicha Ben Lakhdar; Linda Mahjoubi; Emilie Routier; Elisabeth Chachaty; Bertrand Gachot; Stephane De Botton; Jean-Baptiste Micol; Christophe Willekens
Journal:  Infection       Date:  2016-12-01       Impact factor: 3.553

3.  Case Report: Successful Management of Refractory Keratomycosis in an Alpaca Using Penetrating Keratoplasty and Combination Antifungal Therapy (Caspofungin 0.5% and Terbinafine 1%).

Authors:  Braidee C Foote; Joe S Smith; Anna Catherine Bowden; Rachel A Allbaugh; Lionel Sebbag
Journal:  Front Vet Sci       Date:  2021-03-11

4.  Fungal keratitis due to Scopulariopsis brevicaulis and a potential promising therapeutic effect of antibacterial agents: A case report.

Authors:  Nasser M Kaplan; Rami A Al-Dwairi; Nasr N AlRabadi
Journal:  Medicine (Baltimore)       Date:  2021-12-10       Impact factor: 1.817

5.  Rapid Assays for Specific Detection of Fungi of Scopulariopsis and Microascus Genera and Scopulariopsis brevicaulis Species.

Authors:  Milena Kordalewska; Tomasz Jagielski; Anna Brillowska-Dąbrowska
Journal:  Mycopathologia       Date:  2016-06-02       Impact factor: 2.574
  5 in total

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