Literature DB >> 26100506

[Incidental finding of a cardiac paraganglioma].

C M Steger1, G Laufer, P L Moser, F A Offner, N Bonaros.   

Abstract

Cardiac paragangliomas are extremely rare neoplasms with an incidence of 1% of all cardiac tumors and can be completely asymptomatic, therefore, diagnosis is difficult. This article reports the case of an 18-year-old man with a heart murmur detected during a routine physical examination. Echocardiography revealed a heart tumor measuring 7 cm in size in the right atrium. Due to the tumor size and the threat of tricuspid valve insufficiency, tumor resection was performed. The histopathological examination revealed a cardiac paraganglioma with positive reactions of the tumor cells for chromogranin A, synaptophysin and CD56. Differentiating a primary cardiac paraganglioma from other more common cardiac tumors and particularly from metastases of neuroendocrine neoplasms from other locations is essential not only for the further clinical treatment but also for the prognosis of the patient.

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Year:  2015        PMID: 26100506     DOI: 10.1007/s00292-015-0039-6

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  4 in total

Review 1.  Cardiac pheochromocytomas.

Authors:  V A Jebara; M S Uva; A Farge; C Acar; M Azizi; P F Plouin; P Corvol; J C Chachques; P Dervanian; J N Fabiani
Journal:  Ann Thorac Surg       Date:  1992-02       Impact factor: 4.330

2.  An intrapericardial phaeochromocytoma.

Authors:  E Besterman; L L Bromley; W S Peart
Journal:  Br Heart J       Date:  1974-03

3.  Cardiac paraganglioma presenting with acute myocardial infarction and stroke.

Authors:  Emil R Hayek; Michael M Hughes; Eric D Speakman; Hugh J Miller; Patrick J Stocker
Journal:  Ann Thorac Surg       Date:  2007-05       Impact factor: 4.330

Review 4.  The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications.

Authors:  C A Stratakis; J A Carney
Journal:  J Intern Med       Date:  2009-07       Impact factor: 8.989

  4 in total
  1 in total

1.  Unusual cardiac paraganglioma mimicking an atypical carcinoid tumor of the lung.

Authors:  Dean Spencer; Mark Evans; Beverly Wang; J Lawrence Delrosario; Timmy Cheng; Jeffrey Milliken
Journal:  J Thorac Dis       Date:  2018-01       Impact factor: 2.895

  1 in total

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