| Literature DB >> 26100506 |
C M Steger1, G Laufer, P L Moser, F A Offner, N Bonaros.
Abstract
Cardiac paragangliomas are extremely rare neoplasms with an incidence of 1% of all cardiac tumors and can be completely asymptomatic, therefore, diagnosis is difficult. This article reports the case of an 18-year-old man with a heart murmur detected during a routine physical examination. Echocardiography revealed a heart tumor measuring 7 cm in size in the right atrium. Due to the tumor size and the threat of tricuspid valve insufficiency, tumor resection was performed. The histopathological examination revealed a cardiac paraganglioma with positive reactions of the tumor cells for chromogranin A, synaptophysin and CD56. Differentiating a primary cardiac paraganglioma from other more common cardiac tumors and particularly from metastases of neuroendocrine neoplasms from other locations is essential not only for the further clinical treatment but also for the prognosis of the patient.Entities:
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Year: 2015 PMID: 26100506 DOI: 10.1007/s00292-015-0039-6
Source DB: PubMed Journal: Pathologe ISSN: 0172-8113 Impact factor: 1.011