Literature DB >> 26099535

Synthesis of a novel series of fluoroarene derivatives of artemisinin as potent antifungal and anticancer agent.

Pori Buragohain1, Naresh Surineni1, Nabin C Barua2, Purnajyoti D Bhuyan1, Paran Boruah1, Jagat C Borah3, Surbala Laisharm3, Dinesh Singh Moirangthem3.   

Abstract

A series of new fluoroarene derivatives of artemisinin were prepared using Suzuki and Sonogashira cross-coupling reactions. An antifungal and antitumor activity was evaluated against opportunistic pathogen Fusarium oxysporum and Hela cancer cell line. All these derivatives have shown moderate to good activity.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Anticancer; Antifungal; Artemisinin; Fusarium oxysporum; Suzuki cross-coupling

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Substances:

Year:  2015        PMID: 26099535     DOI: 10.1016/j.bmcl.2015.05.067

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

Review 1.  Artemisinin and its derivatives: a potential therapeutic approach for oral lichen planus.

Authors:  Rui-Jie Ma; Ming-Jing He; Ya-Qin Tan; Gang Zhou
Journal:  Inflamm Res       Date:  2019-02-01       Impact factor: 4.575

2.  Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for Ovarian Cancer.

Authors:  Xiaoguang Li; Yu Zhou; Yanling Liu; Xu Zhang; Tao Chen; Kerong Chen; Qian Ba; Jingquan Li; Hong Liu; Hui Wang
Journal:  EBioMedicine       Date:  2016-11-23       Impact factor: 8.143

Review 3.  Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions.

Authors:  Vera A Vil'; Ivan A Yaremenko; Alexey I Ilovaisky; Alexander O Terent'ev
Journal:  Molecules       Date:  2017-11-02       Impact factor: 4.411

4.  Biological activity, quantitative structure-activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs.

Authors:  Isnatin Miladiyah; Jumina Jumina; Sofia Mubarika Haryana; Mustofa Mustofa
Journal:  Drug Des Devel Ther       Date:  2018-01-15       Impact factor: 4.162

  4 in total

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