Literature DB >> 26099427

[Ocular hypertension after intravitreal steroid injections: Clinical update as of 2015].

C Dot1, H El Chehab2, A Russo2, E Agard2.   

Abstract

Intravitreal injections are a therapeutic delivery method best suited to the treatment of retinal diseases. Recent years have been marked by the use of anti-VEGF agents as well as the arrival of sustained-release corticosteroid implants in France, replacing triamcinolone acetonide. A common complication of IVT steroids is secondary ocular hypertension (OHT) resulting from increased outflow resistance. This article summarizes current understanding. OHT induced by topical steroids has been described for 60 years. Intravitreal use also shows a temporary effect if the exposure is short, dose dependence, and varying incidence depending on the drug used. Sustained release formulations and discontinuing treatment have reduced the risk of induced OHT. Risk factors that induce OHT must be clearly identified prior to an injection. Most cases of OHT can be controlled medically, although differences exist between different drugs. In cases where it cannot be controlled, removal of the implant, selective laser trabeculoplasty, and filtration surgery can be discussed.
Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Corticoïdes; Hypertonie oculaire; Injection intra-vitréenne; Intravitreal injection; Ocular hypertension; Steroids

Mesh:

Substances:

Year:  2015        PMID: 26099427     DOI: 10.1016/j.jfo.2015.03.002

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  6 in total

1.  Steroid-induced protracted severe ocular hypertension in a 14-year-old girl.

Authors:  David Cordeiro Sousa; Inês Leal; Luis Abegão Pinto
Journal:  BMJ Case Rep       Date:  2018-06-27

2.  DEX implant intravitreal injection, sustained intraocular hypertension, and steroid-induced glaucoma in patients with no risk factors.

Authors:  Amina Rezkallah; Laurent Kodjikian; Ariane Malclès; Corinne Dot
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-08-11       Impact factor: 3.117

3.  Use of selective laser trabeculoplasty as an alternative in patients who developed ocular hypertension after intravitreal dexamethasone implants: a series of 35 eyes.

Authors:  Jérémy Billant; Emilie Agard; Ikrame Douma; Antoine Levron; Olivier Brunet; Charles-Henry Remignon; Lucas Sejournet; Corinne Dot
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2022-06-04       Impact factor: 3.535

4.  Elevated Intraocular Pressure After Intravitreal Steroid Injection in Diabetic Macular Edema: Monitoring and Management.

Authors:  Francisco J Goñi; Ingeborg Stalmans; Philippe Denis; Jean-Philippe Nordmann; Simon Taylor; Michael Diestelhorst; Antonio R Figueiredo; David F Garway-Heath
Journal:  Ophthalmol Ther       Date:  2016-05-10

5.  Morphological and Functional Outcomes after Intravitreal Dexamethasone Injection for Macular Edema in Patients with Central Vein Occlusion at 48-Week Follow-Up.

Authors:  Cristina Nicula; Dorin Nicula; Anca Rednik; Adriana Bulboaca; Ovidiu Crișan
Journal:  J Ophthalmol       Date:  2020-02-11       Impact factor: 1.909

6.  Intraocular pressure fluctuation following intravitreal dexamethasone implant and incidence of secondary ocular hypertension: a Zambian perspective.

Authors:  Pallavi Raj; Kshitiz Kumar; Santosh Balasubramaniam; Coimbatore Sekar Geetha; Amar Agarwal
Journal:  Pan Afr Med J       Date:  2021-06-06
  6 in total

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