Stefan Stübinger1,2, Anika Drechsler1, Alexander Bürki3, Karina Klein1, Peter Kronen2,4, Brigitte von Rechenberg1,2. 1. Hightech Research Center of Cranio-Maxillofacial Surgery, University of Basel, CH-4031, Basel, Switzerland. 2. Center for Applied Biotechnology and Molecular Medicine (CABMM), Vetsuisse Faculty, University of Zurich, CH-8057, Zurich, Switzerland. 3. Institute for Surgical Biotechnology and Biomechanics, University of Bern, CH-3014, Bern, Switzerland. 4. Veterinary Anaesthesia Services Int (VAS), CH-8400, Winterthur, Switzerland.
Abstract
PURPOSE: The purpose of this study was to evaluate the bone formation capability of polyetheretherketone (PEEK) and carbon fiber-reinforced PEEK (CFR-PEEK) implants coated with different titanium and hydroxyapatite plasma-sprayed layers after 2 and 12 weeks. METHODS: In six sheep 108 implants were placed in the pelvis. Altogether six different surface modifications were tested. After 2 and 12 weeks, n = 3 implants per group were examined histologically and n = 6 implants per group were tested by a pull-out test. RESULTS: Biomechanically (p = 0.001) as well as histologically (p > 0.05) surface coating of PEEK/CFR-PEEK led to an increase of osseointegration from 2 to 12 weeks. After 12 weeks, coated implants demonstrated significant (p < 0.001) higher pull-out values in comparison to uncoated implants. Overall, the double coating (titanium bond layer and hydroxyapatite top layer) showed the most favorable results after 2 and 12 weeks. CONCLUSIONS: Plasma-sprayed titanium and hydroxyapatite coatings on PEEK or CFR-PEEK demonstrated a significant improvement of osseointegration.
PURPOSE: The purpose of this study was to evaluate the bone formation capability of polyetheretherketone (PEEK) and carbon fiber-reinforced PEEK (CFR-PEEK) implants coated with different titanium and hydroxyapatite plasma-sprayed layers after 2 and 12 weeks. METHODS: In six sheep 108 implants were placed in the pelvis. Altogether six different surface modifications were tested. After 2 and 12 weeks, n = 3 implants per group were examined histologically and n = 6 implants per group were tested by a pull-out test. RESULTS: Biomechanically (p = 0.001) as well as histologically (p > 0.05) surface coating of PEEK/CFR-PEEK led to an increase of osseointegration from 2 to 12 weeks. After 12 weeks, coated implants demonstrated significant (p < 0.001) higher pull-out values in comparison to uncoated implants. Overall, the double coating (titanium bond layer and hydroxyapatite top layer) showed the most favorable results after 2 and 12 weeks. CONCLUSIONS: Plasma-sprayed titanium and hydroxyapatite coatings on PEEK or CFR-PEEK demonstrated a significant improvement of osseointegration.
Authors: M A Basso; S Frey; K A Guerriero; B Jarraya; S Kastner; K W Koyano; D A Leopold; K Murphy; C Poirier; W Pope; A C Silva; G Tansey; L Uhrig Journal: Neuroimage Date: 2020-12-24 Impact factor: 6.556
Authors: Sándor Farkasdi; Dávid Pammer; Róbert Rácz; Gergely Hriczó-Koperdák; Bence Tamás Szabó; Csaba Dobó-Nagy; Beáta Kerémi; József Blazsek; Frederic Cuisinier; Gang Wu; Gábor Varga Journal: Clin Oral Investig Date: 2018-10-29 Impact factor: 3.573