| Literature DB >> 26096748 |
Rüdiger Greinert1, Esther de Vries2, Friederike Erdmann3, Carolina Espina3, Anssi Auvinen4, Ausrele Kesminiene3, Joachim Schüz5.
Abstract
Ultraviolet radiation (UVR) is part of the electromagnetic spectrum emitted naturally from the sun or from artificial sources such as tanning devices. Acute skin reactions induced by UVR exposure are erythema (skin reddening), or sunburn, and the acquisition of a suntan triggered by UVR-induced DNA damage. UVR exposure is the main cause of skin cancer, including cutaneous malignant melanoma, basal-cell carcinoma, and squamous-cell carcinoma. Skin cancer is the most common cancer in fair-skinned populations, and its incidence has increased steeply over recent decades. According to estimates for 2012, about 100,000 new cases of cutaneous melanoma and about 22,000 deaths from it occurred in Europe. The main mechanisms by which UVR causes cancer are well understood. Exposure during childhood appears to be particularly harmful. Exposure to UVR is a risk factor modifiable by individuals' behaviour. Excessive exposure from natural sources can be avoided by seeking shade when the sun is strongest, by wearing appropriate clothing, and by appropriately applying sunscreens if direct sunlight is unavoidable. Exposure from artificial sources can be completely avoided by not using sunbeds. Beneficial effects of sun or UVR exposure, such as for vitamin D production, can be fully achieved while still avoiding too much sun exposure and the use of sunbeds. Taking all the scientific evidence together, the recommendation of the 4th edition of the European Code Against Cancer for ultraviolet radiation is: "Avoid too much sun, especially for children. Use sun protection. Do not use sunbeds."Entities:
Keywords: Adverse effects; Europe; Melanoma; Primary prevention; Skin cancer; Sunburn; Tanning; Ultraviolet light; Ultraviolet radiation
Mesh:
Year: 2015 PMID: 26096748 DOI: 10.1016/j.canep.2014.12.014
Source DB: PubMed Journal: Cancer Epidemiol ISSN: 1877-7821 Impact factor: 2.984