Literature DB >> 26096166

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis.

Yu Sun1, Wen-Zhou Liu1, Tao Liu1, Xu Feng1, Nuo Yang1, Hua-Fu Zhou1.   

Abstract

The generic mitogen-activated protein kinases (MAPK) signaling pathway is shared by four distinct cascades, including the extracellular signal-related kinases (ERK1/2), Jun amino-terminal kinases (JNK1/2/3), p38-MAPK and ERK5. Mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK) pathway is reported to be associated with the cell proliferation, differentiation, migration, senescence and apoptosis. The literatures were searched extensively and this review was performed to review the role of MAPK/ERK signaling pathway in cell proliferation, differentiation, migration, senescence and apoptosis.

Entities:  

Keywords:  Extracellular signal-regulated kinase; mitogen-activated protein kinases; signaling pathway

Mesh：

Substances：

Year:  2015        PMID： 26096166     DOI： 10.3109/10799893.2015.1030412

Source DB:  PubMed          Journal:  J Recept Signal Transduct Res        ISSN： 1079-9893            Impact factor:   2.092


  408 in total

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4.  Cell-specific expression of the transcriptional regulator RHAMM provides a timing mechanism that controls appropriate wound re-epithelialization.

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Journal:  J Biol Chem       Date:  2020-03-12       Impact factor: 5.157

5.  Time-course study of high fat diet induced alterations in spatial memory, hippocampal JNK, P38, ERK and Akt activity.

Authors:  Zahra Abbasnejad; Behzad Nasseri; Homeira Zardooz; Rasoul Ghasemi
Journal:  Metab Brain Dis       Date:  2018-12-14       Impact factor: 3.584

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Journal:  Am J Respir Cell Mol Biol       Date:  2019-05       Impact factor: 6.914

Review 7.  State-of-the-art: functional fluorescent probes for bioimaging and pharmacological research.

Authors:  Lu Lu; Zhou-Yue Wu; Xin Li; Feng Han
Journal:  Acta Pharmacol Sin       Date:  2018-11-28       Impact factor: 6.150

8.  Resistance to apoptosis in Leishmania infantum-infected human macrophages: a critical role for anti-apoptotic Bcl-2 protein and cellular IAP1/2.

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Journal:  Clin Exp Med       Date:  2017-12-07       Impact factor: 3.984

9.  Blockade of ERK1/2 by U0126 alleviates uric acid-induced EMT and tubular cell injury in rats with hyperuricemic nephropathy.

Authors:  Min Tao; Yingfeng Shi; Lunxian Tang; Yi Wang; Lu Fang; Wei Jiang; Tao Lin; Andong Qiu; Shougang Zhuang; Na Liu
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10.  Dictyostelium Erk2 is an atypical MAPK required for chemotaxis.

Authors:  David J Schwebs; Miao Pan; Nirakar Adhikari; Nick A Kuburich; Tian Jin; Jeffrey A Hadwiger
Journal:  Cell Signal       Date:  2018-03-15       Impact factor: 4.315
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