Literature DB >> 26095030

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.

Andrej Sali1, Helen M Berman2, Torsten Schwede3, Jill Trewhella4, Gerard Kleywegt5, Stephen K Burley6, John Markley7, Haruki Nakamura8, Paul Adams9, Alexandre M J J Bonvin10, Wah Chiu11, Matteo Dal Peraro12, Frank Di Maio13, Thomas E Ferrin14, Kay Grünewald15, Aleksandras Gutmanas5, Richard Henderson16, Gerhard Hummer17, Kenji Iwasaki18, Graham Johnson19, Catherine L Lawson2, Jens Meiler20, Marc A Marti-Renom21, Gaetano T Montelione22, Michael Nilges23, Ruth Nussinov24, Ardan Patwardhan5, Juri Rappsilber25, Randy J Read26, Helen Saibil27, Gunnar F Schröder28, Charles D Schwieters29, Claus A M Seidel30, Dmitri Svergun31, Maya Topf27, Eldon L Ulrich7, Sameer Velankar5, John D Westbrook2.   

Abstract

Structures of biomolecular systems are increasingly computed by integrative modeling that relies on varied types of experimental data and theoretical information. We describe here the proceedings and conclusions from the first wwPDB Hybrid/Integrative Methods Task Force Workshop held at the European Bioinformatics Institute in Hinxton, UK, on October 6 and 7, 2014. At the workshop, experts in various experimental fields of structural biology, experts in integrative modeling and visualization, and experts in data archiving addressed a series of questions central to the future of structural biology. How should integrative models be represented? How should the data and integrative models be validated? What data should be archived? How should the data and models be archived? What information should accompany the publication of integrative models?
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID: 26095030      PMCID: PMC4933300          DOI: 10.1016/j.str.2015.05.013

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  75 in total

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Review 10.  Principles for Integrative Structural Biology Studies.

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