| Literature DB >> 26094945 |
Anna Di Fiore1, Alessandro Vergara, Marco Caterino, Vincenzo Alterio, Simona M Monti, Joanna Ombouma, Pascal Dumy, Daniela Vullo, Claudiu T Supuran, Jean-Yves Winum, Giuseppina De Simone.
Abstract
Hydroxylamine-O-sulfonamide, a molecule incorporating two zinc-binding groups (ZBGs), has been investigated as a carbonic anhydrase inhibitor (CAI) by means of kinetic, crystallographic and Raman spectroscopy studies, highlighting interesting results on its mechanism of action. These data can be exploited to design new, effective and selective CAIs.Entities:
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Year: 2015 PMID： 26094945 DOI： 10.1039/c5cc03711e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222