M Keles1, F Caglayan2, U Tozoglu3, A Kara4, E Cankaya5, H Dogan6, G E Dogan7, A Uyanik5, B Aydinli8. 1. Department of Nephrology, Faculty of Medicine, Mevlana University, Konya, Turkey. Electronic address: keles.m@gmail.com. 2. Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Ataturk University, Erzurum, Turkey. 3. Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Ataturk University, Erzurum, Turkey; Department of Oral Diagnosis and Radiology, Faculty of Dentistry, Akdeniz University, Antalya, Turkey. 4. Department of Histology and Embryology, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey. 5. Department of Nephrology, Faculty of Medicine, Ataturk University, Erzurum, Turkey. 6. Department of Medical Biology, Faculty of Medicine, Ataturk University, Erzurum, Turkey. 7. Department of Periodontology, Faculty of Dentistry, Ataturk University, Erzurum, Turkey. 8. Department of General Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Abstract
OBJECTIVES: The aim of this study was to investigate quantitative cytologic changes in oral mucosal smears collected from kidney transplant patients by modern stereologic methods. METHODS: We enrolled 32 kidney transplant patients. Smears were obtained from the buccal mucosa transplant patients before and 12 months after kidney transplantation. Smears from each individual were stained using the Papanicolaou method and were analyzed using a stereological method. RESULTS: Statistically, the nuclear volumes and cytoplasmic volumes in the cells of buccal mucosa were markedly higher after kidney transplantation (P < .05). There was a decreased positive cell density in the oral epithelial cells after kidney transplantation compared with before renal transplantation (P < .05). CONCLUSIONS: These findings suggest that there are alterations in the oral epithelial cells after kidney transplantation, which are detectable by microscopy and cytomorphometry.
OBJECTIVES: The aim of this study was to investigate quantitative cytologic changes in oral mucosal smears collected from kidney transplant patients by modern stereologic methods. METHODS: We enrolled 32 kidney transplant patients. Smears were obtained from the buccal mucosa transplant patients before and 12 months after kidney transplantation. Smears from each individual were stained using the Papanicolaou method and were analyzed using a stereological method. RESULTS: Statistically, the nuclear volumes and cytoplasmic volumes in the cells of buccal mucosa were markedly higher after kidney transplantation (P < .05). There was a decreased positive cell density in the oral epithelial cells after kidney transplantation compared with before renal transplantation (P < .05). CONCLUSIONS: These findings suggest that there are alterations in the oral epithelial cells after kidney transplantation, which are detectable by microscopy and cytomorphometry.