Literature DB >> 26091855

Electrical alternans induced by a brief period of myocardial ischemia during percutaneous coronary intervention: The characteristic ECG morphology and relationship to mechanical alternans.

Takeo Oguro1, Masatsune Fujii1, Koichi Fuse1, Minoru Takahashi1, Satoru Fujita1, Hitoshi Kitazawa1, Masahito Sato1, Yoshio Ikeda1, Masaaki Okabe1, Yoshifusa Aizawa2.   

Abstract

BACKGROUND: Electrical alternans (EA) has not been fully studied in the current percutaneous coronary intervention (PCI) procedure.
OBJECTIVE: The purpose of this study was to evaluate visible EA and the morphology of ST segment during PCI.
METHODS: The incidence of visible EA and ST-segment morphology were studied while the coronary artery was occluded for 20 seconds. When data were available, the relationship between EA and blood pressure was analyzed. The clinical and electrocardiographic data were compared with those of the age- and sex-matched controls.
RESULTS: During balloon inflation, visible EA was observed in 5 of 306 patients (1.6%) in the last 2 years. EA was limited to PCI in the proximal left anterior descending artery. The ST segment elevated to 10.1 ± 3.2 mm, followed by an alternating QRS complex with a lower ST segment (5.6 ± 1.9 mm; P = .0047) with characteristic ST-segment morphology, which is known as lambda pattern. The mean age of the 5 patients was 68 ± 20 years, and 4(80%). were men. After the release of inflation, the ST-segment level returned rapidly to baseline, followed by normalization of J point. Compared with controls, the maximal elevated ST segment was significantly higher in patients with EA (5.7 ± 2.7 mm; P = .0028). The occlusion of the proximal left anterior descending artery with more severe ischemia seemed to be a prerequisite for developing EA. A higher ST segment was associated with a lower blood pressure and vice versa.
CONCLUSION: A short period of ischemia during PCI may induce visible EA and alternating QRS complexes with a characteristic ST-segment morphology. A higher ST segment was associated with a lower blood pressure and vice versa.
Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Electrical alternans; Percutaneous coronary intervention; ST-T morphology

Mesh:

Year:  2015        PMID: 26091855     DOI: 10.1016/j.hrthm.2015.06.027

Source DB:  PubMed          Journal:  Heart Rhythm        ISSN: 1547-5271            Impact factor:   6.343


  1 in total

1.  Microvolt QRS Alternans Without Microvolt T-Wave Alternans in Human Cardiomyopathy: A Novel Risk Marker of Late Ventricular Arrhythmias.

Authors:  Adrian Suszko; Sachin Nayyar; Christopher Labos; Kumaraswamy Nanthakumar; Arnold Pinter; Eugene Crystal; Vijay S Chauhan
Journal:  J Am Heart Assoc       Date:  2020-08-18       Impact factor: 5.501

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.