Literature DB >> 26091823

Radiotherapy and immune checkpoint blockade: potential interactions and future directions.

David C Binder1, Yang-Xin Fu2, Ralph R Weichselbaum3.   

Abstract

Combining radiation and immune checkpoint blockade provides synergistic antitumor responses in animal models and a small subset of patients. New preclinical data have provided mechanistic insight into this treatment interaction and identification of therapeutic targets to optimize this approach.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  cancer; immunotherapy; radiation

Mesh：

Substances：

Year:  2015        PMID： 26091823     DOI： 10.1016/j.molmed.2015.05.007

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  14 in total

1.  [Stereotactic radiotherapy augments the immune response].

Authors:  Esther G C Troost
Journal:  Strahlenther Onkol       Date:  2016-01       Impact factor: 3.621

2.  Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.

Authors:  Annelise G Snyder; Nicholas W Hubbard; Michelle N Messmer; Sigal B Kofman; Cassidy E Hagan; Susana L Orozco; Kristy Chiang; Brian P Daniels; David Baker; Andrew Oberst
Journal:  Sci Immunol       Date:  2019-06-21

Review 3.  PD-1/PD-L1 inhibitors in multiple myeloma: The present and the future.

Authors:  T Jelinek; R Hajek
Journal:  Oncoimmunology       Date:  2016-11-08       Impact factor: 8.110

Review 4.  Blood-based biomarkers for precision medicine in lung cancer: precision radiation therapy.

Authors:  Dirk De Ruysscher; Jianyue Jin; Tim Lautenschlaeger; Jin-Xiong She; Zhongxing Liao; Feng-Ming Spring Kong
Journal:  Transl Lung Cancer Res       Date:  2017-12

5.  Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.

Authors:  Weimin Wang; Ilona Kryczek; Lubomír Dostál; Heng Lin; Lijun Tan; Lili Zhao; Fujia Lu; Shuang Wei; Tomasz Maj; Dongjun Peng; Gong He; Linda Vatan; Wojciech Szeliga; Rork Kuick; Jan Kotarski; Rafał Tarkowski; Yali Dou; Ramandeep Rattan; Adnan Munkarah; J Rebecca Liu; Weiping Zou
Journal:  Cell       Date:  2016-04-28       Impact factor: 41.582

Review 6.  Nanoparticle-Mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy.

Authors:  Xiaopin Duan; Christina Chan; Wenbin Lin
Journal:  Angew Chem Int Ed Engl       Date:  2018-11-15       Impact factor: 15.336

7.  Construction of a metabolomics profile of arsenic trioxide effect in gastric carcinoma cell line SGC7901.

Authors:  Ziqing Chen; Hainan Zhang; Lina Yang; Hewei Jiang; Shujuan Guo; Yang Li; Shengce Tao
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2016-04-03       Impact factor: 3.848

Review 8.  Next-generation sequencing: hype and hope for development of personalized radiation therapy?

Authors:  Ingeborg Tinhofer; Franziska Niehr; Robert Konschak; Sandra Liebs; Matthias Munz; Albrecht Stenzinger; Wilko Weichert; Ulrich Keilholz; Volker Budach
Journal:  Radiat Oncol       Date:  2015-08-28       Impact factor: 3.481

9.  High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.

Authors:  Xue Chen; Qi Zhang; Youjun Luo; Caixia Gao; Xibing Zhuang; Guoxiong Xu; Tiankui Qiao
Journal:  Onco Targets Ther       Date:  2016-10-21       Impact factor: 4.147

Review 10.  Update on PD-1/PD-L1 Inhibitors in Multiple Myeloma.

Authors:  Tomas Jelinek; Bruno Paiva; Roman Hajek
Journal:  Front Immunol       Date:  2018-11-16       Impact factor: 7.561
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