Literature DB >> 26091570

Topical therapies for skin cancer and actinic keratosis.

Tasnuva Haque1, Khondaker M Rahman2, David E Thurston2, Jonathan Hadgraft1, Majella E Lane3.   

Abstract

The global incidence of skin cancer and actinic keratosis (AK) has increased dramatically in recent years. Although many tumours are treated with surgery or radiotherapy topical therapy has a place in the management of certain superficial skin neoplasms and AK. This review considers skin physiology, non-melanoma skin cancer (NMSC), the relationship between AK and skin cancer and drugs administered topically for these conditions. The dermal preparations for management of NMSC and AK are discussed in detail. Notably few studies have examined drug disposition in cancerous skin or in AK. Finally, recent novel approaches for targeting of drugs to skin neoplasms and AK are discussed.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Actinic keratosis; Cancer; Formulation; Melanoma; Skin; Topical

Mesh：

Substances：

Year:  2015        PMID： 26091570     DOI： 10.1016/j.ejps.2015.06.013

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN： 0928-0987            Impact factor:   4.384


  8 in total

Review 1.  Effects of Non-Opioid Analgesics on the Cell Membrane of Skin and Gastrointestinal Cancers.

Authors:  Natalia Janicka; Agnieszka Sałek; Magdalena Sawińska; Ernest Kuchar; Anna Wiela-Hojeńska; Katarzyna Karłowicz-Bodalska
Journal:  Int J Mol Sci       Date:  2022-06-26       Impact factor: 6.208

2.  Diclofenac sodium gel therapy as an alternative to actinic cheilitis.

Authors:  Amanda Katarinny Goes Gonzaga; Patrícia Teixeira de Oliveira; Éricka Janine Dantas da Silveira; Lélia Maria Guedes Queiroz; Ana Miryam Costa de Medeiros
Journal:  Clin Oral Investig       Date:  2017-10-06       Impact factor: 3.573

Review 3.  Vitamin D and Vitamin D Analogs as Adjuncts to Field Therapy Treatments for Actinic Keratoses: Current Research and Future Approaches.

Authors:  Zafer Sattouf; Steven J Repas; Jeffrey B Travers; Craig A Rohan
Journal:  J Skin Cancer       Date:  2021-06-19

4.  MAL Daylight Photodynamic Therapy for Actinic Keratosis: Clinical and Imaging Evaluation by 3D Camera.

Authors:  Carmen Cantisani; Giovanni Paolino; Giovanni Pellacani; Dario Didona; Marco Scarno; Valentina Faina; Tommaso Gobello; Stefano Calvieri
Journal:  Int J Mol Sci       Date:  2016-07-11       Impact factor: 5.923

5.  UK-based prospective cohort study to anglicise and validate the FACE-Q Skin Cancer Module in patients with facial skin cancer undergoing surgical reconstruction: the PROMISCR (Patient-Reported Outcome Measure in Skin Cancer Reconstruction) study.

Authors:  Thomas Dobbs; Hayley A Hutchings; Iain S Whitaker
Journal:  BMJ Open       Date:  2017-09-24       Impact factor: 2.692

6.  Factors influencing response to ingenol mebutate therapy for actinic keratosis of face and scalp.

Authors:  Nevena Skroza; Ilaria Proietti; Nicoletta Bernardini; Veronica Balduzzi; Alessandra Mambrin; Anna Marchesiello; Ersilia Tolino; Sara Zuber; Giuseppe La Torre; Concetta Potenza
Journal:  World J Clin Oncol       Date:  2017-10-10

7.  pH-Responsive Nanostructures Based on Surface Active Fatty Acid-Protic Ionic Liquids for Imiquimod Delivery in Skin Cancer Topical Therapy.

Authors:  Silvia Tampucci; Lorenzo Guazzelli; Susi Burgalassi; Sara Carpi; Patrizia Chetoni; Andrea Mezzetta; Paola Nieri; Beatrice Polini; Christian Silvio Pomelli; Eleonora Terreni; Daniela Monti
Journal:  Pharmaceutics       Date:  2020-11-11       Impact factor: 6.321

Review 8.  Gene Regulations upon Hydrogel-Mediated Drug Delivery Systems in Skin Cancers-An Overview.

Authors:  Ramya Mathiyalagan; Anjali Kariyarath Valappil; Deok Chun Yang; Se Chan Kang; Thavasyappan Thambi
Journal:  Gels       Date:  2022-09-02
  8 in total

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