Literature DB >> 26091339

PARPs and ADP-Ribosylation: 50 Years … and Counting.

W Lee Kraus1.   

Abstract

Over 50 years ago, the discovery of poly(ADP-ribose) (PAR) set a new field of science in motion-the field of poly(ADP-ribosyl) transferases (PARPs) and ADP-ribosylation. The field is still flourishing today. The diversity of biological processes now known to require PARPs and ADP-ribosylation was practically unimaginable even two decades ago. From an initial focus on DNA damage detection and repair in response to genotoxic stresses, the field has expanded to include the regulation of chromatin structure, gene expression, and RNA processing in a wide range of biological systems, including reproduction, development, aging, stem cells, inflammation, metabolism, and cancer. This special focus issue of Molecular Cell includes a collection of three Reviews, three Perspectives, and a SnapShot, which together summarize the current state of the field and suggest where it may be headed.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26091339      PMCID： PMC4477203          DOI： 10.1016/j.molcel.2015.06.006

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  65 in total

1.  Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-robose) by a calf thymus extract.

Authors:  M Miwa; T Sugimura
Journal:  J Biol Chem       Date:  1971-10-25       Impact factor: 5.157

2.  Studies on the polymer of adenosine diphosphate ribose. II. Characterization of the polymer.

Authors:  R H Reeder; K Ueda; T Honjo; Y Nishizuka; O Hayaishi
Journal:  J Biol Chem       Date:  1967-07-10       Impact factor: 5.157

3.  The polymerization of adenosine 5'-diphosphate-ribose moiety of NAD by nuclear enzyme. II. Properties of the reaction product.

Authors:  S Hasegawa; S Fujimura; Y Shimizu; R Sugimura
Journal:  Biochim Biophys Acta       Date:  1967-12-19

4.  Polymerization of the adenosine 5'-diphosphate ribose moiety of NAD by rat liver nuclear enzyme.

Authors:  T Sugimura; S Fujimura; S Hasegawa; Y Kawamura
Journal:  Biochim Biophys Acta       Date:  1967-04-18

5.  Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei.

Authors:  Y Nishizuka; K Ueda; K Nakazawa; O Hayaishi
Journal:  J Biol Chem       Date:  1967-07-10       Impact factor: 5.157

6.  Polymerization of the adenosine 5'-diphosphate-ribose moiety of nicotinamide-adenine dinucleotide by nuclear enzyme. I. Enzymatic reactions.

Authors:  S Fujimura; S Hasegawa; Y Shimizu; T Sugimura
Journal:  Biochim Biophys Acta       Date:  1967-09-26

7.  Purification and properties of glycohydrolase from calf thymus splitting ribose-ribose linkages of poly(adenosine diphosphate ribose).

Authors:  M Miwa; M Tanaka; T Matsushima; T Sugimura
Journal:  J Biol Chem       Date:  1974-06-10       Impact factor: 5.157

Review 8.  Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.

Authors:  Eva Barkauskaite; Gytis Jankevicius; Ivan Ahel
Journal:  Mol Cell       Date:  2015-06-18       Impact factor: 17.970

Review 9.  The PARP superfamily.

Authors:  Jean-Christophe Amé; Catherine Spenlehauer; Gilbert de Murcia
Journal:  Bioessays       Date:  2004-08       Impact factor: 4.345

10.  Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

Authors:  Ulrich Cortes; Wei-Min Tong; Donna L Coyle; Mirella L Meyer-Ficca; Ralph G Meyer; Virginie Petrilli; Zdenko Herceg; Elaine L Jacobson; Myron K Jacobson; Zhao-Qi Wang
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272
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  59 in total

Review 1.  Double-barreled gun: Combination of PARP inhibitor with conventional chemotherapy.

Authors:  Yanxin Lu; Yang Liu; Ying Pang; Karel Pacak; Chunzhang Yang
Journal:  Pharmacol Ther       Date:  2018-04-03       Impact factor: 12.310

Review 2.  Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

Authors:  Nathan A Berger; Valerie C Besson; A Hamid Boulares; Alexander Bürkle; Alberto Chiarugi; Robert S Clark; Nicola J Curtin; Salvatore Cuzzocrea; Ted M Dawson; Valina L Dawson; György Haskó; Lucas Liaudet; Flavio Moroni; Pál Pacher; Peter Radermacher; Andrew L Salzman; Solomon H Snyder; Francisco Garcia Soriano; Robert P Strosznajder; Balázs Sümegi; Raymond A Swanson; Csaba Szabo
Journal:  Br J Pharmacol       Date:  2017-03-26       Impact factor: 8.739

3.  Plants get on PAR with poly(ADP-ribosyl)ation.

Authors:  Frank Lh Menke
Journal:  EMBO Rep       Date:  2016-11-02       Impact factor: 8.807

4.  Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.

Authors:  Chun-Song Yang; Kasey Jividen; Adam Spencer; Natalia Dworak; Li Ni; Luke T Oostdyk; Mandovi Chatterjee; Beata Kuśmider; Brian Reon; Mahmut Parlak; Vera Gorbunova; Tarek Abbas; Erin Jeffery; Nicholas E Sherman; Bryce M Paschal
Journal:  Mol Cell       Date:  2017-05-18       Impact factor: 17.970

5.  Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress.

Authors:  Nathan P Westcott; Joseph P Fernandez; Henrik Molina; Howard C Hang
Journal:  Nat Chem Biol       Date:  2017-01-16       Impact factor: 15.040

6.  Metastatic Prostate Cancer in a RAD51C Mutation Carrier.

Authors:  Bindu R Potugari; Jessica M Engel; Adedayo A Onitilo
Journal:  Clin Med Res       Date:  2018-12

7.  PARylation of the forkhead-associated domain protein DAWDLE regulates plant immunity.

Authors:  Baomin Feng; Shisong Ma; Sixue Chen; Ning Zhu; Shuxin Zhang; Bin Yu; Yu Yu; Brandon Le; Xuemei Chen; Savithramma P Dinesh-Kumar; Libo Shan; Ping He
Journal:  EMBO Rep       Date:  2016-10-18       Impact factor: 8.807

Review 8.  The NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning.

Authors:  Nathalie Khoury; Kevin B Koronowski; Juan I Young; Miguel A Perez-Pinzon
Journal:  Antioxid Redox Signal       Date:  2017-08-07       Impact factor: 8.401

Review 9.  Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.

Authors:  Marco Raffaele Cosenza; Alwin Krämer
Journal:  Chromosome Res       Date:  2016-01       Impact factor: 5.239

10.  Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress.

Authors:  Xiao Fu; Chunyan Zhang; Hao Meng; Kai Zhang; Lei Shi; Cheng Cao; Ye Wang; Chao Su; Lingbiao Xin; Yuanyuan Ren; Wei Zhang; Xiaoming Sun; Lin Ge; Olli Silvennoinen; Zhi Yao; Xi Yang; Jie Yang
Journal:  Cell Death Differ       Date:  2018-02-19       Impact factor: 15.828
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