| Literature DB >> 26091029 |
Christopher S Garris1, Mikael J Pittet2.
Abstract
XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth. In this issue of Cell, Cubillos-Ruiz et al. demonstrate that XBP1 in tumor-infiltrating dendritic cells blunts anti-tumor immunity. These findings further imply XBP1 as a relevant target for cancer therapy.Entities:
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Year: 2015 PMID： 26091029 DOI： 10.1016/j.cell.2015.06.006
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582