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Literature DB >> 26091028

Healing the NIH-Funded Biomedical Research Enterprise.

Abstract

Many feel that the R01 grant system supporting biomedical research in the U.S. is broken, discouraging entry of young investigators into the system and inadequately supporting more established investigators. Here, I argue for a "person-not-project"-based scheme that would permit creative, unfettered research by new investigators, better tie ongoing research contributions to continued funding, and help match the number of investigators seeking support with available funds.

Entities: CellLine Disease Gene Species

Mesh：

Year: 2015 PMID： 26091028 PMCID： PMC4495897 DOI： 10.1016/j.cell.2015.05.052

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

6 in total

1. Reforming science: methodological and cultural reforms.

Authors: Arturo Casadevall; Ferric C Fang
Journal: Infect Immun Date: 2011-12-19 Impact factor: 3.441

2. A generation at risk: young investigators and the future of the biomedical workforce.

Authors: Ronald J Daniels
Journal: Proc Natl Acad Sci U S A Date: 2015-01-05 Impact factor: 11.205

3. Opinion: Addressing systemic problems in the biomedical research enterprise.

Authors: Bruce Alberts; Marc W Kirschner; Shirley Tilghman; Harold Varmus
Journal: Proc Natl Acad Sci U S A Date: 2015-02-17 Impact factor: 11.205

4. Funding. NIH institute considers broad shift to 'people' awards.

Authors: Jocelyn Kaiser
Journal: Science Date: 2014-07-25 Impact factor: 47.728

5. Rescuing US biomedical research from its systemic flaws.

Authors: Bruce Alberts; Marc W Kirschner; Shirley Tilghman; Harold Varmus
Journal: Proc Natl Acad Sci U S A Date: 2014-04-14 Impact factor: 11.205

6. Maximizing the return on taxpayers' investments in fundamental biomedical research.

Authors: Jon R Lorsch
Journal: Mol Biol Cell Date: 2015-05-01 Impact factor: 4.138

6 in total

9 in total

8. How much would each researcher receive if competitive government research funding were distributed equally among researchers?

Authors: Krist Vaesen; Joel Katzav
Journal: PLoS One Date: 2017-09-08 Impact factor: 3.240

9. Outcomes of early NIH-funded investigators: Experience of the National Institute of Allergy and Infectious Diseases.

Authors: Patricia A Haggerty; Matthew J Fenton
Journal: PLoS One Date: 2018-09-12 Impact factor: 3.240

9 in total

Healing the NIH-Funded Biomedical Research Enterprise.

1. Reforming science: methodological and cultural reforms.

2. A generation at risk: young investigators and the future of the biomedical workforce.

3. Opinion: Addressing systemic problems in the biomedical research enterprise.

4. Funding. NIH institute considers broad shift to 'people' awards.

5. Rescuing US biomedical research from its systemic flaws.

6. Maximizing the return on taxpayers' investments in fundamental biomedical research.

1. Epidemiology at a time for unity.

Review 2. The Last 50 Years: Mismeasurement and Mismanagement Are Impeding Scientific Research.

3. NIH peer review percentile scores are poorly predictive of grant productivity.

4. What's Fair Is Fair: Leveling the Playing Field for Young Scientists.

5. Supporting novel biomedical research via multilayer collaboration networks.

6. How to get and keep your lab funded.

7. Why can't we make research grant allocation systems more consistent? A personal opinion.

8. How much would each researcher receive if competitive government research funding were distributed equally among researchers?

9. Outcomes of early NIH-funded investigators: Experience of the National Institute of Allergy and Infectious Diseases.