Literature DB >> 2608891

[Initial results of high-dose-rate afterloading treatment of tumors in the head and neck region].

A Brock, H A Gitt, S Pohlmann, W Prager.   

Abstract

First results of high-dose-rate afterloading therapy in the head-neck area are encouraging. The procedure is not very invasive and is suitable especially for older patients, not tolerating much, who can be hardly submitted another therapeutic method. The limited spatial dose distribution allows a careful treatment of the surrounding tissue in spite of the application of high single doses, however limits the size of tumors too, that the afterloading therapy is possible in (max. 2 cm). The method represents an alternative of the much more complicated procedure of the low-dose contact therapy, that affects the patients in a stronger way like interstitial therapy and moulage treatment. No tumor recurrences or metastasis were seen in our patients. Influence of alteration in fractionation rhythm and of application of sources with very high dose capacity will be the subject of further studies.

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Mesh:

Year:  1989        PMID: 2608891

Source DB:  PubMed          Journal:  Radiobiol Radiother (Berl)        ISSN: 0033-8184


  2 in total

1.  [Salvage therapy of advanced squamous cell carcinoma of the mouth cavity and oropharynx. Results of interstitial high-dose-rate brachytherapy combined with ablative tumor surgery].

Authors:  R E Friedrich; A Krüll; R Schwarz; H Thurmann; K Plambeck; R Schmelzle
Journal:  Strahlenther Onkol       Date:  1997-10       Impact factor: 3.621

2.  [The indications for and results of HDR afterloading therapy in diseases of the skin and mucosa with standardized surface applicators (the Leipzig applicator)].

Authors:  A Köhler-Brock; W Prager; S Pohlmann; S Kunze
Journal:  Strahlenther Onkol       Date:  1999-04       Impact factor: 3.621

  2 in total

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