Literature DB >> 26088800

AmyLoad: website dedicated to amyloidogenic protein fragments.

Pawel P Wozniak1, Malgorzata Kotulska1.   

Abstract

UNLABELLED: Analyses of amyloidogenic sequence fragments are essential in studies of neurodegenerative diseases. However, there is no one internet dataset that collects all the sequences that have been investigated for their amyloidogenicity. Therefore, we have created the AmyLoad website which collects the amyloidogenic sequences from all major sources. The website allows for filtration of the fragments and provides detailed information about each of them. Registered users can both personalize their work with the website and submit their own sequences into the database. To maintain database reliability, submitted sequences are reviewed before making them available to the public. Finally, we re-implemented several amyloidogenic sequence predictors, thus the AmyLoad website can be used as a sequence analysis tool. We encourage researchers working on amyloid proteins to contribute to our service.
AVAILABILITY AND IMPLEMENTATION: The AmyLoad website is freely available at http://comprec-lin.iiar.pwr.edu.pl/amyload/. CONTACT: malgorzata.kotulska@pwr.edu.pl.
© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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Year:  2015        PMID: 26088800     DOI: 10.1093/bioinformatics/btv375

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  17 in total

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Journal:  Protein Sci       Date:  2017-07-15       Impact factor: 6.725

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Authors:  Boris Haimov; Simcha Srebnik
Journal:  Biophys J       Date:  2018-04-10       Impact factor: 4.033

3.  Bioinformatics Methods in Predicting Amyloid Propensity of Peptides and Proteins.

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Review 4.  Protein aggregation: in silico algorithms and applications.

Authors:  R Prabakaran; Puneet Rawat; A Mary Thangakani; Sandeep Kumar; M Michael Gromiha
Journal:  Biophys Rev       Date:  2021-01-17

5.  AmyPro: a database of proteins with validated amyloidogenic regions.

Authors:  Mihaly Varadi; Greet De Baets; Wim F Vranken; Peter Tompa; Rita Pancsa
Journal:  Nucleic Acids Res       Date:  2018-01-04       Impact factor: 16.971

6.  Quantiprot - a Python package for quantitative analysis of protein sequences.

Authors:  Bogumił M Konopka; Marta Marciniak; Witold Dyrka
Journal:  BMC Bioinformatics       Date:  2017-07-17       Impact factor: 3.169

7.  The amyloid interactome: Exploring protein aggregation.

Authors:  Konstantina V Biza; Katerina C Nastou; Paraskevi L Tsiolaki; Chara V Mastrokalou; Stavros J Hamodrakas; Vassiliki A Iconomidou
Journal:  PLoS One       Date:  2017-03-01       Impact factor: 3.240

8.  Variability of Amyloid Propensity in Imperfect Repeats of CsgA Protein of Salmonella enterica and Escherichia coli.

Authors:  Natalia Szulc; Marlena Gąsior-Głogowska; Jakub W Wojciechowski; Monika Szefczyk; Andrzej M Żak; Michał Burdukiewicz; Malgorzata Kotulska
Journal:  Int J Mol Sci       Date:  2021-05-12       Impact factor: 5.923

9.  Solubility and Aggregation of Selected Proteins Interpreted on the Basis of Hydrophobicity Distribution.

Authors:  Magdalena Ptak-Kaczor; Mateusz Banach; Katarzyna Stapor; Piotr Fabian; Leszek Konieczny; Irena Roterman
Journal:  Int J Mol Sci       Date:  2021-05-08       Impact factor: 5.923

10.  Amyloidogenic motifs revealed by n-gram analysis.

Authors:  Michał Burdukiewicz; Piotr Sobczyk; Stefan Rödiger; Anna Duda-Madej; Paweł Mackiewicz; Małgorzata Kotulska
Journal:  Sci Rep       Date:  2017-10-11       Impact factor: 4.379

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