Literature DB >> 26088125

A retrospective analysis to identify the factors affecting infection in patients undergoing chemotherapy.

Ji Hyun Park1, Hyeon-Young Kim2, Hanna Lee3, Eun Kyoung Yun4.   

Abstract

PURPOSE: This study compares the performance of the logistic regression and decision tree analysis methods for assessing the risk factors for infection in cancer patients undergoing chemotherapy.
METHOD: The subjects were 732 cancer patients who were receiving chemotherapy at K university hospital in Seoul, Korea. The data were collected between March 2011 and February 2013 and were processed for descriptive analysis, logistic regression and decision tree analysis using the IBM SPSS Statistics 19 and Modeler 15.1 programs.
RESULTS: The most common risk factors for infection in cancer patients receiving chemotherapy were identified as alkylating agents, vinca alkaloid and underlying diabetes mellitus. The logistic regression explained 66.7% of the variation in the data in terms of sensitivity and 88.9% in terms of specificity. The decision tree analysis accounted for 55.0% of the variation in the data in terms of sensitivity and 89.0% in terms of specificity. As for the overall classification accuracy, the logistic regression explained 88.0% and the decision tree analysis explained 87.2%.
CONCLUSIONS: The logistic regression analysis showed a higher degree of sensitivity and classification accuracy. Therefore, logistic regression analysis is concluded to be the more effective and useful method for establishing an infection prediction model for patients undergoing chemotherapy.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Chemotherapy; Decision tree; Infection; Logistic regression

Mesh:

Year:  2015        PMID: 26088125     DOI: 10.1016/j.ejon.2015.03.006

Source DB:  PubMed          Journal:  Eur J Oncol Nurs        ISSN: 1462-3889            Impact factor:   2.398


  3 in total

Review 1.  Glycemic Excursion, Adverse Drug Reactions, and Self-Management in Diabetes Patients Undergoing Chemotherapy: A Literature Review.

Authors:  Naoko Terao; Kumi Suzuki
Journal:  Asia Pac J Oncol Nurs       Date:  2021-10-04

2.  Glycosylated haemoglobin and prognosis in 10,536 people with cancer and pre-existing diabetes: a meta-analysis with dose-response analysis.

Authors:  Suping Ling; Michael Sweeting; Francesco Zaccardi; David Adlam; Umesh T Kadam
Journal:  BMC Cancer       Date:  2022-10-06       Impact factor: 4.638

Review 3.  Importance of Glycemic Control in Cancer Patients with Diabetes: Treatment through End of Life.

Authors:  Denise Soltow Hershey
Journal:  Asia Pac J Oncol Nurs       Date:  2017 Oct-Dec
  3 in total

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