Mingxin Zhou1, Yao Zhou2, Qiuling Song3. 1. Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China), Fax: (+86) 592-6162990. 2. College of Materials Science & Engineering, Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China). 3. Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China), Fax: (+86) 592-6162990. qsong@hqu.edu.cn.
Abstract
A domino Knoevenagel-decarboxylation-alkene difunctionalization sequence has been developed for the conversion of benzaldehydes into β-ketophosphonates, catalyzed by a cooperative Cu/Fe system, whereby C-P and C=O bonds are formed simultaneously in a one-pot reaction. The reaction proceeds in good yields and with a broad substrate scope and environmentally benign conditions.
A domino Knoevenagel-decarboxylation-alkene difunctionalization sequence has been developed for the conversion of pan class="Chemical">benzaldehydes into β-ketophosphonates, catalyzed by a cooperative Cu/Fe system, whereby C-P and C=O bonds are formed simultaneously in a one-pot reaction. The reaction proceeds in good yields and with a broad substrate scope and environmentally benign conditions.