Literature DB >> 26086775

Occupational contact allergy to methylchloroisothiazolinone/methylisothiazolinone and methylisothiazolinone.

Anna-Reetta Vauhkala1,2, Maria Pesonen1, Sari Suomela1, Outi Kuuliala1, Katri Suuronen1, Kristiina Aalto-Korte1.   

Abstract

BACKGROUND: Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI are common preservatives in industrial and household products and in cosmetics. Occupational contact allergy to MCI/MI or MI has been reported among painters and paint factory workers in particular.
OBJECTIVES: To retrospectively describe patients with occupational contact allergy to MCI/MI and MI at the Finnish Institute of Occupational Health (FIOH).
METHODS: Patch test files and clinical records of patients examined at the FIOH between January 2002 and February 2013 were reviewed to identify the patients.
RESULTS: Seventy-two of 1745 patients showed positive reactions to MCI/MI and/or MI. Of these, 36 were occupational cases, and 31 were diagnosed during the second half of the study period. Hairdressers and beauticians, mechanics and repairmen, and machinists were the most significant occupational groups, followed by painters and paint factory workers, and café and restaurant workers.
CONCLUSIONS: We observed a sixfold increase in the number of occupational cases in the second half of the study period as compared with the first half. Liquid soaps and industrial hand cleansers were common sources of exposure to MCI/MI or MI. A total of 33% of the patients used products without any mention of MCI/MI or MI in safety data sheets or product declarations.
© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  beauticians; detergents; fountain solution; hairdressers; hand cleansers; liquid soaps; machinists; mechanics and repairmen; metalworking fluids; shampoos

Mesh:

Substances:

Year:  2015        PMID: 26086775     DOI: 10.1111/cod.12413

Source DB:  PubMed          Journal:  Contact Dermatitis        ISSN: 0105-1873            Impact factor:   6.600


  4 in total

1.  Isothiazolinone Content of US Consumer Adhesives: Ultrahigh-Performance Liquid Chromatographic Mass Spectrometry Analysis.

Authors:  Molly C Goodier; Lun-Yi Zang; Paul D Siegel; Erin M Warshaw
Journal:  Dermatitis       Date:  2019 Mar/Apr       Impact factor: 4.845

2.  Contact allergy to preservatives in patients with occupational contact dermatitis and exposure analysis of preservatives in registered chemical products for occupational use.

Authors:  Jakob Ferløv Schwensen; Ulrik Fischer Friis; Torkil Menné; Mari-Ann Flyvholm; Jeanne Duus Johansen
Journal:  Int Arch Occup Environ Health       Date:  2017-02-06       Impact factor: 3.015

3.  Isothiazolinone in Residential Interior Wall Paint: A High-Performance Liquid Chromatographic-Mass Spectrometry Analysis.

Authors:  Molly C Goodier; Paul D Siegel; Lun-Yi Zang; Erin M Warshaw
Journal:  Dermatitis       Date:  2018 Nov/Dec       Impact factor: 4.845

4.  Mixture Toxicity of Methylisothiazolinone and Propylene Glycol at a Maximum Concentration for Personal Care Products.

Authors:  Juyoung Park; Handule Lee; Kwangsik Park
Journal:  Toxicol Res       Date:  2018-10-15
  4 in total

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