Literature DB >> 26085738

HELLP or Help: A Real Challenge.

Sushil Chawla1, Ashish Marwaha1, Raju Agarwal1.   

Abstract

OBJECTIVES: To ascertain the prevalence, presentation, diagnosis, severity, and complications of HELLP syndrome.
MATERIALS AND METHODS: This is a prospective observational study analyzing the conditions and the data of 24 cases of HELLP syndrome in a tertiary care hospital. The analysis was done for the demographic characteristics, presentation of these patients, complications associated, and the perinatal outcome.
RESULTS: 0.45 % of the patients admitted for delivery developed HELLP syndrome. Majority of the patients developed the condition in 30-36 weeks period of gestation, while five patients developed it in the postpartum period. The condition led to 12.5 % of maternal and 45.8 % of perinatal mortality.
CONCLUSION: HELLP syndrome is an important cause for maternal and perinatal morbidity and mortality.

Entities:  

Keywords:  HELLP Syndrome; Maternal mortality; Severe pre-eclampsia

Year:  2014        PMID: 26085738      PMCID: PMC4464564          DOI: 10.1007/s13224-014-0582-8

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  9 in total

Review 1.  A review of HELLP syndrome.

Authors:  W M Curtin; L Weinstein
Journal:  J Perinatol       Date:  1999-03       Impact factor: 2.521

2.  Intravascular hemolysis, thrombocytopenia and other hematologic abnormalities associated with severe toxemia of pregnancy.

Authors:  J A PRITCHARD; R WEISMAN; O D RATNOFF; G J VOSBURGH
Journal:  N Engl J Med       Date:  1954-01-21       Impact factor: 91.245

3.  Risk factors for post-partum complications occurring after preeclampsia and HELLP syndrome. A study in 453 consecutive pregnancies.

Authors:  Philippe Deruelle; Elodie Coudoux; Anne Ego; Véronique Houfflin-Debarge; Xavier Codaccioni; Damien Subtil
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2005-08-22       Impact factor: 2.435

4.  Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy. 1982.

Authors:  Louis Weinstein
Journal:  Am J Obstet Gynecol       Date:  2005-09       Impact factor: 8.661

5.  Maternal and neonatal outcome of pregnancies complicated with maternal HELLP syndrome.

Authors:  D S Raval; S Co; M A Reid; R Pildes
Journal:  J Perinatol       Date:  1997 Jul-Aug       Impact factor: 2.521

6.  Maternal mortality associated with HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

Authors:  C M Isler; B K Rinehart; D A Terrone; R W Martin; E F Magann; J N Martin
Journal:  Am J Obstet Gynecol       Date:  1999-10       Impact factor: 8.661

Review 7.  HELLP syndrome: the state of the art.

Authors:  Jason K Baxter; Louis Weinstein
Journal:  Obstet Gynecol Surv       Date:  2004-12       Impact factor: 2.347

8.  Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

Authors:  B M Sibai; M K Ramadan; I Usta; M Salama; B M Mercer; S A Friedman
Journal:  Am J Obstet Gynecol       Date:  1993-10       Impact factor: 8.661

Review 9.  Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count.

Authors:  Baha M Sibai
Journal:  Obstet Gynecol       Date:  2004-05       Impact factor: 7.661

  9 in total

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