Literature DB >> 26084187

[Intervention effect of Tibetan patent medicine Ruyi Zhenbao pills in acute ischemic stroke in rats].

Rui-ying Liu, Wei-jie Wu, Rui Tan, Bin Xie, Zhen-dong Zhong, Jing-ping He, Yao Chen, Xin-li Kang.   

Abstract

Ischemic stroke is a primary cause of death and long-term disability all over the world. This disease is resulted from ischemia and hypoxia in brain tissues because of insufficient blood supply and causes a series of physiochemical metabolism disorders and physiological dysfunction. Its high disability ratio has bright huge burdens to society, governments and families. However, there is not efficacious medicine to treat it. In this study, a right middle cerebral artery occlusion was established in rats to observe the multi-path and multi-aspect intervention effects of Tibetan patent medicine Ruyi Zhenbao pills in reducing injuries to Nissl bodies, cerebral edema and inflammatory reactions and preventing cellular apoptosis, in order to lay a foundation for defining its therapeutic mechanism in acute ischemic stroke.

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Year:  2015        PMID: 26084187

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  2 in total

1.  Study and exploration of the pharmacokinetics of traditional Tibetan medicine Ruyi Zhenbao tablets after single and long-term administration.

Authors:  Hongping Hou; Tengfei Chen; Ziying Xu; Zihui Yu; Caixia Wang; Rongxia Liu; Bo Peng; Wei Yang; Feng Li; Xiangyi Che; Bing Li; Yu Wang; Ling Song; Yunhang Gao; Zuguang Ye; Guangping Zhang
Journal:  Front Pharmacol       Date:  2022-09-29       Impact factor: 5.988

2.  Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1/miR-214/HSP27 axis.

Authors:  Yongxiong He; Mingdong Li; Bokang Lv; Yanqiang Huan; Bin Liu; Dongsheng Wang; Hai Yu; Liansheng Zhang; Zhiqiang Shi
Journal:  Biosci Rep       Date:  2018-11-07       Impact factor: 3.840

  2 in total

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