Literature DB >> 26083887

Mortality predictors of epilepsy and epileptic seizures among hospitalized elderly.

Telma M R Assis1, Aroldo Bacellar1, Gersonita Costa1, Osvaldo J M Nascimento2.   

Abstract

UNLABELLED: Epilepsy and epileptic seizures are common brain disorders in the elderly and are associated with increased mortality that may be ascribed to the underlying disease or epilepsy-related causes.
OBJECTIVE: To describe mortality predictors of epilepsy and epileptic seizures in elderly inpatients.
METHOD: Retrospective analysis was performed on hospitalized elderly who had epilepsy or epileptic seizures, from January 2009 to December 2010. One hundred and twenty patients were enrolled.
RESULTS: The most common etiology was ischemic stroke (37%), followed by neoplasias (13%), hemorrhagic stroke (12%), dementias (11.4%) and metabolic disturbances (5.5%). In a univariate analysis, disease duration (p = 0.04), status epilepticus (p < 0.001) and metabolic etiology (p = 0.005) were associated with mortality. However after adjustment by logistic regression, only status epilepticus remained an independent predictor of death (odds ratio = 13; 95%CI = 2.3 to 72; p = 0.004).
CONCLUSION: In this study status epilepticus was an independent risk factor for death during hospitalization.

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Year:  2015        PMID: 26083887     DOI: 10.1590/0004-282X20150043

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  4 in total

1.  Visualizing prolonged hyperperfusion in post-stroke epilepsy using postictal subtraction SPECT.

Authors:  Kazuki Fukuma; Katsufumi Kajimoto; Tomotaka Tanaka; Shigetoshi Takaya; Katsuya Kobayashi; Akihiro Shimotake; Riki Matsumoto; Akio Ikeda; Kazunori Toyoda; Masafumi Ihara
Journal:  J Cereb Blood Flow Metab       Date:  2020-02-16       Impact factor: 6.200

Review 2.  The causes of new-onset epilepsy and seizures in the elderly.

Authors:  Shasha Liu; Weihua Yu; Yang Lü
Journal:  Neuropsychiatr Dis Treat       Date:  2016-06-17       Impact factor: 2.570

3.  mTOR is involved in stroke-induced seizures and the anti-seizure effect of mild hypothermia.

Authors:  Guo-Shuai Yang; Xiao-Yan Zhou; Xue-Fang An; Xuan-Jun Liu; Yan-Jun Zhang; Dan Yu
Journal:  Mol Med Rep       Date:  2018-02-22       Impact factor: 2.952

4.  Hospital Mortality Among Elderly Patients Admitted With Neurological Disorders Was Not Predicted by any Particular Diagnosis in a Tertiary Medical Center.

Authors:  Aroldo Bacellar; Telma Assis; Bruno B Pedreira; Gersonita Costa; Osvaldo J M Nascimento
Journal:  Open Neurol J       Date:  2018-01-22
  4 in total

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