| Literature DB >> 26083574 |
H De Backer1, K Darquennes, C Dooms, J Yserbyt, J Coolen, J Verschakelen, E Verbeken, I Vrints, W Wuyts.
Abstract
Pulmonary alveolar (phospholipo)proteinosis (PAP) is a rare lung disease, predominantly autoimmune in nature. This case report describes a patient with insidious dyspnoea since 5 years and a milky appearance of her bronchoalveolar fluid, leading to the diagnosis of PAP. The onset of symptoms coincided with an exchange of her silicone breast implants. Giant cell reaction in axillary adenopathies pointed towards silicone leakage. Adjuvants, such as silicone, might boost pre-existing antigen reactions of the immune system, potentially leading to autoimmune phenomena.Entities:
Keywords: Autoimmune/inflammatory; Autoimmunity; Pulmonary alveolar proteinosis; Silicone; Syndrome induced by adjuvants
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Year: 2015 PMID: 26083574 DOI: 10.1179/2295333715Y.0000000035
Source DB: PubMed Journal: Acta Clin Belg ISSN: 1784-3286 Impact factor: 1.264