Literature DB >> 26082346

An acoustofluidic sputum liquefier.

Po-Hsun Huang1, Liqiang Ren, Nitesh Nama, Sixing Li, Peng Li, Xianglan Yao, Rosemarie A Cuento, Cheng-Hsin Wei, Yuchao Chen, Yuliang Xie, Ahmad Ahsan Nawaz, Yael G Alevy, Michael J Holtzman, J Philip McCoy, Stewart J Levine, Tony Jun Huang.   

Abstract

We demonstrate the first microfluidic-based on-chip liquefaction device for human sputum samples. Our device is based on an acoustofluidic micromixer using oscillating sharp edges. This acoustofluidic sputum liquefier can effectively and uniformly liquefy sputum samples at a throughput of 30 μL min(-1). Cell viability and integrity are maintained during the sputum liquefaction process. Our acoustofluidic sputum liquefier can be conveniently integrated with other microfluidic units to enable automated on-chip sputum processing and analysis.

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Year:  2015        PMID： 26082346      PMCID： PMC6518399          DOI： 10.1039/c5lc00539f

Source DB:  PubMed          Journal:  Lab Chip        ISSN： 1473-0189            Impact factor:   6.799


  28 in total

1.  A spatiotemporally controllable chemical gradient generator via acoustically oscillating sharp-edge structures.

Authors:  Po-Hsun Huang; Chung Yu Chan; Peng Li; Nitesh Nama; Yuliang Xie; Cheng-Hsin Wei; Yuchao Chen; Daniel Ahmed; Tony Jun Huang
Journal:  Lab Chip       Date:  2015-09-04       Impact factor: 6.799

2.  Probing Cell Deformability via Acoustically Actuated Bubbles.

Authors:  Yuliang Xie; Nitesh Nama; Peng Li; Zhangming Mao; Po-Hsun Huang; Chenglong Zhao; Francesco Costanzo; Tony Jun Huang
Journal:  Small       Date:  2015-12-30       Impact factor: 13.281

3.  Acoustofluidic devices controlled by cell phones.

Authors:  Hunter Bachman; Po-Hsun Huang; Shuaiguo Zhao; Shujie Yang; Peiran Zhang; Hai Fu; Tony Jun Huang
Journal:  Lab Chip       Date:  2018-01-30       Impact factor: 6.799

4.  Applications of Acoustofluidics in Bioanalytical Chemistry.

Authors:  Peng Li; Tony Jun Huang
Journal:  Anal Chem       Date:  2018-12-18       Impact factor: 6.986

5.  Investigation of micromixing by acoustically oscillated sharp-edges.

Authors:  Nitesh Nama; Po-Hsun Huang; Tony Jun Huang; Francesco Costanzo
Journal:  Biomicrofluidics       Date:  2016-04-13       Impact factor: 2.800

6.  An acoustofluidic device for efficient mixing over a wide range of flow rates.

Authors:  Hunter Bachman; Chuyi Chen; Joseph Rufo; Shuaiguo Zhao; Shujie Yang; Zhenhua Tian; Nitesh Nama; Po-Hsun Huang; Tony Jun Huang
Journal:  Lab Chip       Date:  2020-02-27       Impact factor: 6.799

7.  Acoustofluidic methods in cell analysis.

Authors:  Yuliang Xie; Hunter Bachman; Tony Jun Huang
Journal:  Trends Analyt Chem       Date:  2019-07-13       Impact factor: 12.296

8.  On-chip stool liquefaction via acoustofluidics.

Authors:  Shuaiguo Zhao; Weihua He; Zhehan Ma; Peiyao Liu; Po-Hsun Huang; Hunter Bachman; Lin Wang; Shujie Yang; Zhenhua Tian; Zeyu Wang; Yuyang Gu; Zhemiao Xie; Tony Jun Huang
Journal:  Lab Chip       Date:  2019-03-13       Impact factor: 6.799

9.  Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders.

Authors:  Mary Emma Gorham Bigelow; Brian G Jamieson; Chi On Chui; Yufei Mao; Kyeong-Sik Shin; Tony Jun Huang; Po-Hsun Huang; Liqiang Ren; Bishow Adhikari; Jue Chen; Erin Iturriaga
Journal:  IEEE J Transl Eng Health Med       Date:  2016-07-22       Impact factor: 3.316

10.  Acoustofluidic Transfer of Inflammatory Cells from Human Sputum Samples.

Authors:  Sixing Li; Liqiang Ren; Po-Hsun Huang; Xianglan Yao; Rosemarie A Cuento; J Philip McCoy; Craig E Cameron; Stewart J Levine; Tony Jun Huang
Journal:  Anal Chem       Date:  2016-05-16       Impact factor: 6.986
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