Literature DB >> 26081455

Dietary modification and supplementation for the treatment of age-related macular degeneration.

Geoffrey K Broadhead1, John R Grigg2, Andrew A Chang2, Peter McCluskey2.   

Abstract

Age-related macular degeneration (AMD) causes a significant proportion of visual loss in the developed world. Currently, little is known about its pathogenesis, and treatment options are limited. Dietary intake is one of the few modifiable risk factors for this condition. The best-validated therapies remain oral antioxidant supplements based on those investigated in the Age-Related Eye Disease Study (AREDS) and the recently completed Age-Related Eye Disease Study 2 (AREDS2). In this review, current dietary guidelines related to AMD, along with the underlying evidence to support them, are presented in conjunction with current treatment recommendations. Both AREDS and AREDS2 are discussed, as are avenues for further research, including supplementation with vitamin D and saffron. Despite the considerable disease burden of atrophic AMD, few effective therapies are available to treat it, and further research is required.
© The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Age-related macular degeneration; antioxidants; diet; dietary supplements.

Mesh：

Substances：

Year:  2015        PMID： 26081455     DOI： 10.1093/nutrit/nuv005

Source DB:  PubMed          Journal:  Nutr Rev        ISSN： 0029-6643            Impact factor:   7.110


  18 in total

Review 1.  Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.

Authors:  Jennifer R Evans; John G Lawrenson
Journal:  Cochrane Database Syst Rev       Date:  2017-07-31

Review 2.  Adherence to the Mediterranean-Style Eating Pattern and Macular Degeneration: A Systematic Review of Observational Studies.

Authors:  Annalisa Gastaldello; Francesca Giampieri; José L Quiles; María D Navarro-Hortal; Silvia Aparicio; Eduardo García Villena; Kilian Tutusaus Pifarre; Rachele De Giuseppe; Giuseppe Grosso; Danila Cianciosi; Tamara Y Forbes-Hernández; Seyed M Nabavi; Maurizio Battino
Journal:  Nutrients       Date:  2022-05-12       Impact factor: 6.706

3.  Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death.

Authors:  Rodrigo Meléndez García; David Arredondo Zamarripa; Edith Arnold; Xarubet Ruiz-Herrera; Ramsés Noguez Imm; German Baeza Cruz; Norma Adán; Nadine Binart; Juan Riesgo-Escovar; Vincent Goffin; Benito Ordaz; Fernando Peña-Ortega; Ataúlfo Martínez-Torres; Carmen Clapp; Stéphanie Thebault
Journal:  EBioMedicine       Date:  2016-04-20       Impact factor: 8.143

Review 4.  Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review.

Authors:  Ângela Carneiro; José Paulo Andrade
Journal:  Oxid Med Cell Longev       Date:  2017-01-05       Impact factor: 6.543

5.  Combined influence of poor health behaviours on the prevalence and 15-year incidence of age-related macular degeneration.

Authors:  Bamini Gopinath; Gerald Liew; Victoria M Flood; Nichole Joachim; George Burlutsky; Paul Mitchell
Journal:  Sci Rep       Date:  2017-06-28       Impact factor: 4.379

6.  Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.

Authors:  Manas R Biswal; Pingyang Han; Ping Zhu; Zhaoyang Wang; Hong Li; Cristhian J Ildefonso; Alfred S Lewin
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-02-01       Impact factor: 4.799

7.  Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models.

Authors:  Jan Tode; Elisabeth Richert; Stefan Koinzer; Alexa Klettner; Claus von der Burchard; Ralf Brinkmann; Ralph Lucius; Johann Roider
Journal:  Transl Vis Sci Technol       Date:  2018-05-01       Impact factor: 3.283

Review 8.  Saffron (Crocus sativus L.) in Ocular Diseases: A Narrative Review of the Existing Evidence from Clinical Studies.

Authors:  Rebekka Heitmar; James Brown; Ioannis Kyrou
Journal:  Nutrients       Date:  2019-03-18       Impact factor: 5.717

9.  Exploration of the Effect and Mechanism of Fructus Lycii, Rehmanniae Radix Praeparata, and Paeonia lactiflora in the Treatment of AMD Based on Network Pharmacology and in vitro Experimental Verification.

Authors:  Xi Chen; Jing Zuo; Tianming Hu; Xiaoqing Shi; Yujie Zhu; Hao Wu; Ying Xia; Wei Shi; Wei Wei
Journal:  Drug Des Devel Ther       Date:  2021-06-28       Impact factor: 4.162

Review 10.  Vitamin D and Age-Related Macular Degeneration.

Authors:  Alfredo Garcia Layana; Angelo Maria Minnella; Gerhard Garhöfer; Tariq Aslam; Frank G Holz; Anita Leys; Rufino Silva; Cécile Delcourt; Eric Souied; Johanna M Seddon
Journal:  Nutrients       Date:  2017-10-13       Impact factor: 5.717
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