| Literature DB >> 26080739 |
Meng Wang1, Bang-Wei Yu2, Mei-Hua Yu1, Li-Xin Gao2, Jing-Ya Li2, He-Yao Wang2, Jia Li2, Ai-Jun Hou3.
Abstract
Two new isoprenylated flavonoids, laevigasins A and B (1 and 2, resp.), and one new isoprenylated 2-arylbenzofuran, leavigasin C (3), together with eight known compounds, 4-11, were isolated from the twigs of Morus laevigata. Their structures were elucidated by spectroscopic methods. Laevigasin A (1) showed significant inhibitory effect on α-glucosidase in vitro. Notabilisin E (5), taxifolin (10), and hultenin (11) inhibited PTP1B phosphatase activity in vitro.Entities:
Keywords: Flavonoids; Isoprenylated phenolics; Laevigasins A and B; Leavigasin C; Morus laevigata; Protein tyrosine phosphatase 1B; α-Glucosidase
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Year: 2015 PMID： 26080739 DOI： 10.1002/cbdv.201400210
Source DB: PubMed Journal: Chem Biodivers ISSN： 1612-1872 Impact factor: 2.408