A K Regan1, C C Blyth2, L Tracey3, D B Mak3, P C Richmond2, P V Effler4. 1. School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, WA, Australia; Communicable Disease Control Directorate, Western Australia Department of Health, Shenton Park, WA, Australia. Electronic address: Annette.Regan@health.wa.gov.au. 2. School of Paediatrics and Child Health, University of Western Australia, Crawley, WA, Australia; Vaccine Trials Group, Telethon Kids Institute, University of Western Australia, Subiaco, WA, Australia. 3. Communicable Disease Control Directorate, Western Australia Department of Health, Shenton Park, WA, Australia. 4. School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, WA, Australia; Communicable Disease Control Directorate, Western Australia Department of Health, Shenton Park, WA, Australia.
Abstract
OBJECTIVES: In 2013, the Follow-up and Active Surveillance of Trivalent Influenza Vaccine in Mums (FASTMum) program began using short message service (SMS) to collect adverse event information in pregnant women who recently receivedtrivalent influenza vaccine (TIV). This study was designed to compare data collected via SMS and telephone for the purposes of monitoring vaccine safety. METHODS: A number of 344 women who received TIV were randomly assigned to a telephone interview group. They were telephoned seven days post-vaccination and administered a standard survey soliciting any adverse events following immunisation (AEFI) they experienced. They were matched by brand of vaccine, age group, and residence to 344 women who were sent a SMS seven days post-vaccination. The SMS solicited similar information. AEFI reported by SMS and telephone interview were compared by calculating risk ratios. RESULTS:Response rate was higher to SMS compared to telephone interview (90.1% vs. 63.9%). Women who were surveyed by SMS were significantly less likely to report an AEFI compared to women who were surveyed by telephone (RR: 0.41; 95% CI: 0.29-0.59). The greatest discrepancies between SMS and telephone interview were for self-reported injection site reactions (3.1% vs. 16.8%) and unsolicited (or "other") events (11.4% vs. 4.1%). Data collected by SMS was significantly timelier. CONCLUSIONS: Data collection by SMS results in significantly improved response rates and timeliness of vaccine safety data. Systems which incorporate SMS could be used to more rapidly detect safety signals and promote more rapid public health response to vaccine quality issues. Crown
RCT Entities:
OBJECTIVES: In 2013, the Follow-up and Active Surveillance of Trivalent Influenza Vaccine in Mums (FASTMum) program began using short message service (SMS) to collect adverse event information in pregnant women who recently received trivalent influenza vaccine (TIV). This study was designed to compare data collected via SMS and telephone for the purposes of monitoring vaccine safety. METHODS: A number of 344 women who received TIV were randomly assigned to a telephone interview group. They were telephoned seven days post-vaccination and administered a standard survey soliciting any adverse events following immunisation (AEFI) they experienced. They were matched by brand of vaccine, age group, and residence to 344 women who were sent a SMS seven days post-vaccination. The SMS solicited similar information. AEFI reported by SMS and telephone interview were compared by calculating risk ratios. RESULTS: Response rate was higher to SMS compared to telephone interview (90.1% vs. 63.9%). Women who were surveyed by SMS were significantly less likely to report an AEFI compared to women who were surveyed by telephone (RR: 0.41; 95% CI: 0.29-0.59). The greatest discrepancies between SMS and telephone interview were for self-reported injection site reactions (3.1% vs. 16.8%) and unsolicited (or "other") events (11.4% vs. 4.1%). Data collected by SMS was significantly timelier. CONCLUSIONS: Data collection by SMS results in significantly improved response rates and timeliness of vaccine safety data. Systems which incorporate SMS could be used to more rapidly detect safety signals and promote more rapid public health response to vaccine quality issues. Crown
Authors: Pasquale Stefanizzi; Sara De Nitto; Giuseppe Spinelli; Sabrina Lattanzio; Paolo Stella; Domenica Ancona; Maria Dell'Aera; Margherita Padovano; Savino Soldano; Silvio Tafuri; Francesco Paolo Bianchi Journal: Vaccines (Basel) Date: 2021-05-04