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Literature DB >> 26079081

Cytoskeletal chirality: swirling cells tell left from right.

Abstract

A new study reports that dynamic actin fibers in cells on circular islands self-organize into a swirling counter-clockwise pattern and describes a basic cytoskeletal mechanism for the establishment of left-right asymmetry that is based on myosin contraction and twisting of the formin-actin filament.

Mesh：

Substances：
Actins

Year: 2015 PMID： 26079081 DOI： 10.1016/j.cub.2015.04.039

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

4 in total

1. Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog.

Authors: Angus Davison; Gary S McDowell; Jennifer M Holden; Harriet F Johnson; Georgios D Koutsovoulos; M Maureen Liu; Paco Hulpiau; Frans Van Roy; Christopher M Wade; Ruby Banerjee; Fengtang Yang; Satoshi Chiba; John W Davey; Daniel J Jackson; Michael Levin; Mark L Blaxter
Journal: Curr Biol Date: 2016-02-25 Impact factor: 10.834

Cytoskeletal chirality: swirling cells tell left from right.

1. Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog.

2. Chirality provides a direct fitness advantage and facilitates intermixing in cellular aggregates.

Review 3. Cell chirality in cardiovascular development and disease.

4. All-Dielectric Chiral Metasurfaces Based on Crossed-Bowtie Nanoantennas.