Literature DB >> 26078698

Cardiovascular side effects related with use of synthetic cannabinoids "bonzai" : two case reports.

Sezen Ugan Atik1, Reyhan Dedeoğlu1, Fatih Varol2, Halit Çam2, Ayşe Güler Eroğlu1, Levent Saltık1.   

Abstract

Information about the effects of synthetic cannabinoids "bonzai" on the cardiovascular system is limited. In this article, two patients in whom different cardiological side effects were observed following use of synthetic cannabinoids 'bonzai' were presented. Our first patient who was a 16-year old boy presented to pediatric emergency department with severe chest pain which had started one hour before. On electrocardiographic examination, ST segment elevations greater than 3 mm were observed in DII, DIII, AVF and V5-V6 derivations which caused to suspicious myocardial infarction. Cardiac catheterization was performed and coronary angiographic findings were found to be normal. When the patient was questioned again, it was learned that he used synthetic cannabinoid 'bonzai'. The second patient who was aged 18 years and addicted to synthetic cannabinoid 'bonzai' was brought to our emergency department by his friends because of clouding of consciousness. Dopamine treatment was started in the patient whose cardiac apical beat reduced to 40/min and who was found to develop hypertension, because bradycardia worsened. However, the blood pressure increased rapidly and dopamine treatment was stopped. Heart rate and blood pressure monitoring was continued. Use of synthetic cannabinoids 'bonzai' should be kept in mind in patients who present to emergency departments with chest pain and complaints related with the cardiovascular system.

Entities:  

Keywords:  Synthetic cannabinoids; bradycardia; myocardial infaction

Year:  2015        PMID: 26078698      PMCID: PMC4462325          DOI: 10.5152/tpa.2015.2609

Source DB:  PubMed          Journal:  Turk Pediatri Ars


  9 in total

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3.  Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings.

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Review 4.  Acute cardiovascular fatalities following cannabis use.

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Review 5.  A new face of endocannabinoids in pharmacotherapy. Part I: protective role of endocannabinoids in hypertension and myocardial infarction.

Authors:  M Zubrzycki; A Liebold; A Janecka; M Zubrzycka
Journal:  J Physiol Pharmacol       Date:  2014-04       Impact factor: 3.011

6.  [Significance of cardiac cannabinoid receptors in regulation of cardiac rhythm, myocardial contractility, and electrophysiologic processes in heart].

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Journal:  Izv Akad Nauk Ser Biol       Date:  2007 Jan-Feb

7.  Review of detection frequency and type of synthetic cannabinoids in herbal compounds analyzed by Istanbul Narcotic Department of the Council of Forensic Medicine, Turkey.

Authors:  Fatma Gurdal; Mahmut Asirdizer; Rezzan Gulhan Aker; Senol Korkut; Yasemin Gocer; E Esra Kucukibrahimoglu; C Haluk Ince
Journal:  J Forensic Leg Med       Date:  2013-04-28       Impact factor: 1.614

Review 8.  Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.

Authors:  Marisol S Castaneto; David A Gorelick; Nathalie A Desrosiers; Rebecca L Hartman; Sandrine Pirard; Marilyn A Huestis
Journal:  Drug Alcohol Depend       Date:  2014-08-18       Impact factor: 4.492

9.  A Unique Case of Cardiac Arrest following K2 Abuse.

Authors:  Saif Ibrahim; Farah Al-Saffar; Thomas Wannenburg
Journal:  Case Rep Cardiol       Date:  2014-05-25
  9 in total
  7 in total

Review 1.  Effects of Cannabis on Cardiovascular System: The Good, the Bad, and the Many Unknowns.

Authors:  Ali E Dabiri; Ghassan S Kassab
Journal:  Med Cannabis Cannabinoids       Date:  2021-11-12

Review 2.  What is the Current Knowledge About the Cardiovascular Risk for Users of Cannabis-Based Products? A Systematic Review.

Authors:  Emilie Jouanjus; Valentin Raymond; Maryse Lapeyre-Mestre; Valérie Wolff
Journal:  Curr Atheroscler Rep       Date:  2017-06       Impact factor: 5.113

Review 3.  Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly.

Authors:  Pal Pacher; Sabine Steffens; György Haskó; Thomas H Schindler; George Kunos
Journal:  Nat Rev Cardiol       Date:  2017-09-14       Impact factor: 32.419

Review 4.  Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health.

Authors:  Aviv M Weinstein; Paola Rosca; Liana Fattore; Edythe D London
Journal:  Front Psychiatry       Date:  2017-08-23       Impact factor: 4.157

5.  Disseminated Intravascular Coagulopathy Secondary to Unintentional Brodifacoum Poisoning via Synthetic Marijuana.

Authors:  Abigail Chan; Michael Adashek; Julian Kang; Adriana Medina
Journal:  J Hematol (Brossard)       Date:  2019-03-30

6.  Concomitant Substance Use Increases the Toxic Effect of synthetic cannabinoid (Bonsai): A Prospective Study.

Authors:  İnan Beydilli; Murat Duyan; Fevzi Yılmaz; Engin Deniz Arslan; İlhan Korkmaz; Mehmet Akçimen; Mustafa Keşaplı; Arefe İmak; Umut Cengiz Çakır; Cemil Kavalcı; Ertan Ararat; Hamit Ellidağ
Journal:  Acta Biomed       Date:  2020-08-25

Review 7.  Cardiovascular Complications of Marijuana and Related Substances: A Review.

Authors:  Amitoj Singh; Sajeev Saluja; Akshat Kumar; Sahil Agrawal; Munveer Thind; Sudip Nanda; Jamshid Shirani
Journal:  Cardiol Ther       Date:  2017-12-07
  7 in total

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