Literature DB >> 26078683

Evaluation of neurological and cardiological findings in carbonmonoxide poisoning in children.

Hatice Boztepe1, Zahide Yalaki1, Yıldız Dallar Bilge1.   

Abstract

AIM: The aim of our study was to investigate the relation of blood carboxyhemoglobin level with presentation finding and clinical properties and to demonstrate neurological and cardiological findings which are indicators of tissue hypoxia in patients followed up because of carbonmonoxide (CO) poisoning.
MATERIAL AND METHODS: Three hundred and twenty-five patients who were followed up because of carbonmonoxide poisoning between 2011 and 2013 in our pediatric emergency department were evaluated prospectively. Ethics committee approval was obtained for the study on 10.19.2011 (number: 0437). The carbonmonoxide levels, source of intoxication, neurological and cardiological findings and treatment methods were recorded. Blood gases and cardiac enzymes were studied and electrocardiography (ECG) was performed. The data were analysed using SPSS for windows 16.0 package program.
RESULTS: One hundred and sixty-eight (51.7%) of the patients were female and the median age was 9 years (11 days-17 years). Two hundred and twenty-eight (70.2%) of the patients were poisoned while using heater and 78.1% presented during winter months. The median carbonmonoxide level of the patients was found to be 24.8%. Cardiac enzymes were found to be increased in 10.5% of the patients, first degree A-V block was found in 0.6% and negative T wave was found in 0.3%. Glasgow coma score was found to be below 14 in 4.6% of the patients. A significant correlation was found between the carboxyhemoglobin levels and neurological findings, cardiological findings and lactate (p<0.05). Normobaric oxygen treatment was given to 76.3% of the patients and hyperbaric oxygen treatment was given to 23.7%.
CONCLUSIONS: We think that neurological disorders and cardiac findings may be closely related, since systemic involvement may be easier in carbonmonoxide poisoning in children, Glasgow coma score should be assessed in the follow-up of the patients and cardiac enzymes and serum lactate levels should be monitored closely from the time of presentation.

Entities:  

Keywords:  Child; carbonmonoxide poisoning; cardiological finding; hyperbaric oxygen; neurological finding

Year:  2014        PMID: 26078683      PMCID: PMC4462320          DOI: 10.5152/tpa.2014.201010

Source DB:  PubMed          Journal:  Turk Pediatri Ars


  16 in total

1.  Cardiac damage in pediatric carbon monoxide poisoning.

Authors:  C Gandini; A F Castoldi; S M Candura; S Priori; C Locatelli; R Butera; C Bellet; L Manzo
Journal:  J Toxicol Clin Toxicol       Date:  2001

2.  Questionnaire results of hyperbaric oxygen therapy for acute carbon monoxide poisoning in Japan.

Authors:  Yoko Kusuba; Kenji Taki; Akihide Ohta
Journal:  Undersea Hyperb Med       Date:  2012 Mar-Apr       Impact factor: 0.698

Review 3.  Clinical practice. Carbon monoxide poisoning.

Authors:  Lindell K Weaver
Journal:  N Engl J Med       Date:  2009-03-19       Impact factor: 91.245

4.  Epidemiology of severe carbon monoxide poisoning in children.

Authors:  J A Mendoza; N B Hampson
Journal:  Undersea Hyperb Med       Date:  2006 Nov-Dec       Impact factor: 0.698

5.  Cardiovascular effects of carbon monoxide poisoning.

Authors:  Nihat Kalay; Ibrahim Ozdogru; Yakup Cetinkaya; Namik Kemal Eryol; Ali Dogan; Ibrahim Gul; Tugrul Inanc; Ibrahim Ikizceli; Abdurrahman Oguzhan; Adnan Abaci
Journal:  Am J Cardiol       Date:  2006-11-29       Impact factor: 2.778

6.  Carbon monoxide poisoning in children.

Authors:  Chi-Hsiun Cho; Nan-Chang Chiu; Che-Sheng Ho; Chun-Chih Peng
Journal:  Pediatr Neonatol       Date:  2008-08       Impact factor: 2.083

Review 7.  Carbon monoxide poisoning: a review for clinicians.

Authors:  J Varon; P E Marik; R E Fromm; A Gueler
Journal:  J Emerg Med       Date:  1999 Jan-Feb       Impact factor: 1.484

8.  Lactate as a prognostic factor in carbon monoxide poisoning: a case report.

Authors:  Shigeaki Inoue; Takeshi Saito; Tomoatsu Tsuji; Kozo Tamura; Shiro Ohama; Seiji Morita; Isotoshi Yamamoto; Sadaki Inokuchi
Journal:  Am J Emerg Med       Date:  2008-10       Impact factor: 2.469

9.  Carbon monoxide-related deaths in Ankara between 2001 and 2011.

Authors:  Cem Uysal; Safa Celik; Aynur Duzgun Altuntas; Eyup Kandemir; Mehmet Kaya; Mustafa Karapirli; Sevilay Sezer; Omer Akyol
Journal:  Inhal Toxicol       Date:  2013-02       Impact factor: 2.724

10.  Analysis of the features of acute carbon monoxide poisoning and hyperbaric oxygen therapy in children.

Authors:  Coşkun Yarar; Ayten Yakut; Ahmet Akin; Bilal Yildiz; Ener Cağri Dinleyici
Journal:  Turk J Pediatr       Date:  2008 May-Jun       Impact factor: 0.552

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