Tanju Çelik1, Nazan Savaş2, Selim Kurtoğlu3, Özlem Sangün4, Zeki Aydın5, Didin Mustafa6, Oktay Hasan Öztürk7, Seher Mısırlıoğlu6, Murat Öktem8. 1. Department of Pediatrics, Mustafa Kemal University, Tayfur Ata Sökmen Faculty of Medicine, Hatay, Turkey. 2. Department of Public Health, Mustafa Kemal University, Tayfur Ata Sökmen Faculty of Medicine, Hatay, Turkey. 3. Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey. 4. Clinic of Pediatrics, Hatay Public Hospital, Hatay, Turkey. 5. Division of Chemistry, Mustafa Kemal University Faculty of Arts and Sciences, Hatay, Turkey. 6. Department of Biochemistry, Mustafa Kemal University, Tayfur Ata Sökmen Faculty of Medicine, Hatay, Turkey. 7. Division of Food, Mustafa Kemal University Faculty of Agriculture, Hatay, Turkey. 8. Düzen Laboratory, Biochemistry, Ankara, Turkey.
Abstract
AIM: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiency which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). MATERIAL AND METHODS: This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanışma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. RESULTS: Iodine deficiency was found with a severe (5%), moderate (18.4%) and mild degree (43%), respectively in the village of Tanışma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p<0.001). A significant correlation was found between the levels of iodine, selenium, zinc and molybdenum (p<0.05). A moderately positive correlation was found between iodine and selenium (p<0.001). A moderately positive correlation was found between iodine and zinc levels (p<0.001) and a weak correlation was found between iodine and molybdenum (p<0.01). No significant correlation was found between iodine level and copper level (p>0.05). CONCLUSIONS: Selenium and zinc deficiency may accompany iodine deficiency. Selenium and zinc deficiency should be considered in individuals who are found to have iodine deficiency especially in endemic goitre regions.
AIM: Thyroid diseases related with iodine deficiency are observed commonly in our country and in the world. In this study, we aimed to investigate iodine deficiency in urine and selenium, zinc, copper or molybdenum deficiency which may accompany this in children aged between 6 and 12 years in two schools in the province of Hatay (endemic goitre region). MATERIAL AND METHODS: This study is a case-control field-study in which students aged between 6 and 12 years were included. One hundred fourteen subjects from the village of Tanışma related to the center of our province and 100 subjects from the city center of Hatay (Antakya) were included in the study. Iodine, selenium, zinc, copper and molybdenum levels were measured in the urine samples of the students included in the study. RESULTS:Iodine deficiency was found with a severe (5%), moderate (18.4%) and mild degree (43%), respectively in the village of Tanışma. Mild iodine deficiency (7%) was found in the center of Hatay. No moderate and severe iodine deficiency was found in the control group. A significant difference was found between the groups in terms of urine iodine excretion (p<0.001). A significant correlation was found between the levels of iodine, selenium, zinc and molybdenum (p<0.05). A moderately positive correlation was found between iodine and selenium (p<0.001). A moderately positive correlation was found between iodine and zinc levels (p<0.001) and a weak correlation was found between iodine and molybdenum (p<0.01). No significant correlation was found between iodine level and copper level (p>0.05). CONCLUSIONS:Selenium and zinc deficiency may accompany iodine deficiency. Selenium and zinc deficiency should be considered in individuals who are found to have iodinedeficiency especially in endemic goitre regions.
Entities:
Keywords:
Endemic goitre; iodine deficiency; trace elements
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