Siwei Luo1, Yihua Jiang1, Zhi Liang2, Jiarui Wu3. 1. Hefei National Laboratory for Physical Sciences at Microscale and School of Life Science, University of Science & Technology of China, Hefei, China. 2. Hefei National Laboratory for Physical Sciences at Microscale and School of Life Science, University of Science & Technology of China, Hefei, China liangzhi@ustc.edu.cn wujr@sibs.ac.cn. 3. Hefei National Laboratory for Physical Sciences at Microscale and School of Life Science, University of Science & Technology of China, Hefei, China Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China School of Life Science and Technology, Shanghai Tech University, Shanghai, China Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China liangzhi@ustc.edu.cn wujr@sibs.ac.cn.