Literature DB >> 26074211

Successful treatment of hypertrophic herpes simplex genitalis in HIV-infected patient with topical imiquimod.

Gustavo Deza1, Gemma Martin-Ezquerra1, Laia Curto-Barredo1, Judit Villar García2, Ramon M Pujol1.   

Abstract

Hypertrophic herpes simplex genitalis is an atypical presentation of genital herpes described in the context of immunosuppression, particularly HIV-positive patients. This situation can become a diagnostic and therapeutic challenge. For this reason, alternative therapies are currently being discussed in the literature. We report a case of hypertrophic genital herpes in a HIV-positive patient who was successfully treated with topical 5% imiquimod after treatment failures with oral and i.v. antivirals.
© 2015 Japanese Dermatological Association.

Entities:  

Keywords:  HIV infection; genital ulceration; hypertrophic herpes simplex; imiquimod

Mesh：

Substances：

Year:  2015        PMID： 26074211     DOI： 10.1111/1346-8138.12969

Source DB:  PubMed          Journal:  J Dermatol        ISSN： 0385-2407            Impact factor:   4.005


  6 in total

1.  A case of hypertrophic herpes simplex virus affecting the eyelid and cornea masquerading as IgG4-related disease.

Authors:  Prachi Dua; Roman Shinder; Derek B Laskar; Douglas R Lazzaro; Allison E Rizzuti
Journal:  Am J Ophthalmol Case Rep       Date:  2017-12-13

2.  Leflunomide in the Treatment of a Pseudotumoral Genital Herpes Simplex Virus Infection in an HIV Patient.

Authors:  Marie R Roger; Gregory M Anstead
Journal:  Case Rep Infect Dis       Date:  2017-03-08

Review 3.  Herpes Simplex Virus Evasion of Early Host Antiviral Responses.

Authors:  Eduardo I Tognarelli; Tomás F Palomino; Nicolás Corrales; Susan M Bueno; Alexis M Kalergis; Pablo A González
Journal:  Front Cell Infect Microbiol       Date:  2019-04-30       Impact factor: 5.293

4.  Acyclovir-resistant chronic mucocutaneous herpes with good response to the association with imiquimod in an AIDS patient: case report.

Authors:  Suellen Ramos de Oliveira; Ariane Sponchiado Assoni; Thiago Jeunon de Sousa Vargas; Egon Daxbacher
Journal:  An Bras Dermatol       Date:  2022-01-14       Impact factor: 2.113

5.  Hypertrophic Herpes Simplex Virus Type 1 Infection in a Patient With Acute Myeloid Leukemia.

Authors:  Yusuke Ogawa; Takakazu Higuchi; Ryosuke Koyamada; Satoru Arai; Sadamu Okada
Journal:  J Hematol (Brossard)       Date:  2017-07-20

Review 6.  Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants.

Authors:  Sachin Bhagchandani; Jeremiah A Johnson; Darrell J Irvine
Journal:  Adv Drug Deliv Rev       Date:  2021-05-29       Impact factor: 15.470
  6 in total

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