Literature DB >> 26073249

Successful Treatment with Infliximab for Refractory Uveitis in a Hemodialysis Patient with Behçet's Disease and a Review of the Literature for Infliximab Use in Patients on Hemodialysis.

Izumi Kurata1, Hiroto Tsuboi, Hidenori Takahashi, Saori Abe, Hiroshi Ebe, Shinya Hagiwara, Naoto Umeda, Yuya Kondo, Hiroshi Ogishima, Takeshi Suzuki, Isao Matsumoto, Sujin Hoshi, Tetsuro Oshika, Takayuki Sumida.   

Abstract

A 36-year-old man with a 16-year history of refractory Behçet's disease (BD)-associated uveitis and chronic renal failure requiring hemodialysis suffered from frequent ocular attacks despite treatment with systemic corticosteroids and cyclosporine A. Following infliximab administration, the patient's BD ocular attack score 24 and visual acuity improved. Although he developed mild acute gastroenteritis, he did not experience any other adverse events. In our review of the literature, we identified seven patients on hemodialysis with inflammatory disease successfully treated with infliximab. Infliximab may be effective and safe in cases of BD and other diseases, including in patients under hemodialysis.

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Year:  2015        PMID: 26073249     DOI: 10.2169/internalmedicine.54.4274

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  1 in total

Review 1.  Behçet's Disease and Nervous System Involvement.

Authors:  Murat Kürtüncü; Erdem Tüzün; Gulsen Akman-Demir
Journal:  Curr Treat Options Neurol       Date:  2016-05       Impact factor: 3.598

  1 in total

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