Literature DB >> 26073007

Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages.

Jaeyoung Kwon1, Sunita Basnet1, Jin Woo Lee2, Eun-Kyoung Seo3, Nanzad Tsevegsuren4, Bang Yeon Hwang2, Dongho Lee5.   

Abstract

Three new flavonostilbenes, alopecurones M-O (1-3), were isolated from the root bark of Sophora alopecuroides L. together with 21 known compounds. The structures of the isolated compounds were elucidated by using NMR, MS, and CD spectroscopic data. All isolates were evaluated for their potential to inhibit LPS-induced nitric oxide production in RAW 264.7 cells.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Keywords:  Flavonostilbenes; Nitric oxide production inhibitor; Sophora alopecuroides L.

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Year:  2015        PMID: 26073007     DOI: 10.1016/j.bmcl.2015.05.062

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Total phenolic, flavonoid, alkaloid and iridoid content and preventive effect of Lider-7-tang on lipopolysaccharide-induced acute lung injury in rats.

Authors:  Ch Erdenechimeg; A Guiqide; B Dejidmaa; Ch Chimedragchaa; S Purevsuren
Journal:  Braz J Med Biol Res       Date:  2017-10-19       Impact factor: 2.590

  1 in total

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