Farin Soleimani1, Reza Shervin Badv2, Amin Momayezi3, Akbar Biglarian4, Asghar Marzban5. 1. Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Kodakyar St, Daneshjo Blvd, Evin, P.O Box: 14155-6386, Tehran, Iran. Electronic address: Soleimani_farin@yahoo.com. 2. Tehran University of Medical Science, Children's Medical Center of Excellence, Dr Gharib St, Keshavarz Blvd, P.O Box: 14155-6386, Tehran, Iran. Electronic address: drbadv@zums.ac.ir. 3. Department of Pediatrics, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address: aminmomayezi@yahoo.com. 4. Department of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Koodakyar Street, Daneshjoo Ave, Evin, Tehran 1985713834, Iran. Electronic address: abiglarian@gmail.com. 5. Department of Pediatrics, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address: Dmarzban@gmail.com.
Abstract
BACKGROUND: At a time of increasing high risk neonates, an assessment method is needed that can reliably predict neurological deficits at an early age. AIMS: The objective of this study was to determine whether the assessment of fidgety movements (FMs) will predict the neurological outcome of infants with hypoxic ischemic encephalopathy (HIE). STUDY DESIGN: This study employed a prospective and descriptive plan. SUBJECTS: The study sample consisted of 15 infants (8 male and 7 female) born at term. Video recording of FMs were analyzed at 3 to 5 months' infants, who identified with perinatal asphyxia and neonatal HIE. FMs were classified as present or absent. OUTCOME MEASURES: At 12-18 months age, the infants' developmental outcome was classified as normal or abnormal according to the Infant Neurological International Battery test. "Abnormal outcome" was denoted as poor motor or neurological outcome such as cerebral palsy, whereas "Normal outcome" denotes normal motor and neurological outcomes. RESULTS: The predictive values of FMs were: a sensitivity 0.80 (95% CI: 0.44-0.96), a specificity 1.00 (95% CI: 0.47-1.00), and the accuracy 0.87 (0.57 to 1.00). CONCLUSIONS: FMs assessment improves our ability to predict later neurodevelopmental outcomes in term born children with neonatal HIE.
BACKGROUND: At a time of increasing high risk neonates, an assessment method is needed that can reliably predict neurological deficits at an early age. AIMS: The objective of this study was to determine whether the assessment of fidgety movements (FMs) will predict the neurological outcome of infants with hypoxic ischemicencephalopathy (HIE). STUDY DESIGN: This study employed a prospective and descriptive plan. SUBJECTS: The study sample consisted of 15 infants (8 male and 7 female) born at term. Video recording of FMs were analyzed at 3 to 5 months' infants, who identified with perinatal asphyxia and neonatal HIE. FMs were classified as present or absent. OUTCOME MEASURES: At 12-18 months age, the infants' developmental outcome was classified as normal or abnormal according to the Infant Neurological International Battery test. "Abnormal outcome" was denoted as poor motor or neurological outcome such as cerebral palsy, whereas "Normal outcome" denotes normal motor and neurological outcomes. RESULTS: The predictive values of FMs were: a sensitivity 0.80 (95% CI: 0.44-0.96), a specificity 1.00 (95% CI: 0.47-1.00), and the accuracy 0.87 (0.57 to 1.00). CONCLUSIONS: FMs assessment improves our ability to predict later neurodevelopmental outcomes in term born children with neonatal HIE.
Authors: Carol Nanyunja; Samantha Sadoo; Annettee Nakimuli; Cally J Tann; Ivan Mambule; Sean R Mathieson; Moffat Nyirenda; Emily L Webb; J Mugalu; Nicola J Robertson; A Nabawanuka; Guillaume Gilbert; J Bwambale; Kathryn Martinello; Alan Bainbridge; Samson Lubowa; Latha Srinivasan; H Ssebombo; Cathy Morgan; Cornelia Hagmann; Frances M Cowan; Kirsty Le Doare; Pia Wintermark; Michael Kawooya; Geraldine B Boylan Journal: Gates Open Res Date: 2022-03-03